Influence of the transcription factor RORγt on the development of NKp46+ cell populations in gut and skin

C Luci, A Reynders, II Ivanov, C Cognet, L Chiche… - Nature …, 2009 - nature.com
NKp46 + CD3 − natural killer lymphocytes isolated from blood, lymphoid organs, lung, liver
and uterus can produce granule-dependent cytotoxicity and interferon-γ. Here we identify in …

Modular transcriptional repertoire analyses of adults with systemic lupus erythematosus reveal distinct type I and type II interferon signatures

L Chiche, N Jourde‐Chiche, E Whalen… - Arthritis & …, 2014 - Wiley Online Library
Objective The role of interferon‐α (IFNα) in the pathogenesis of systemic lupus erythematosus
(SLE) is strongly supported by gene expression studies. The aim of this study was to …

[HTML][HTML] Allograft replacement for infrarenal aortic graft infection: early and late results in 179 patients

E Kieffer, D Gomes, L Chiche, MH Fléron… - Journal of vascular …, 2004 - Elsevier
OBJECTIVES: We evaluated early and late results of allograft replacement to treat infrarenal
aortic graft infection in a large number of patients and compared the results in patients who …

Treatment of primary Sjögren syndrome with rituximab: a randomized trial

…, J Sibilia, JE Gottenberg, L Chiche… - Annals of internal …, 2014 - acpjournals.org
Background: Primary Sjögren syndrome (pSS) is an autoimmune disorder characterized by
ocular and oral dryness or systemic manifestations. Objective: To evaluate efficacy and …

IgG4-related systemic disease: features and treatment response in a French cohort: results of a multicenter registry

…, P Sève, M Hamidou, E Andres, S Burtey, L Chiche… - Medicine, 2012 - journals.lww.com
IgG4-related systemic disease is now recognized as a systemic disease that may affect
various organs. The diagnosis is usually made in patients who present with elevated IgG4 in …

Squash Trypsin Inhibitors from Momordica cochinchinensis Exhibit an Atypical Macrocyclic Structure

JF Hernandez, J Gagnon, L Chiche, TM Nguyen… - Biochemistry, 2000 - ACS Publications
Three trypsin inhibitors (TIs), from the seeds of the squash Momordica cochinchinensis (MCo),
have been isolated and purified using gel filtration, ion exchange chromatography, and …

Leiomyosarcoma of the inferior vena cava: experience in 22 cases

…, M Alaoui, JC Piette, P Cacoub, L Chiche - Annals of surgery, 2006 - journals.lww.com
From 1979 to 2004, 22 patients were seen with leiomyosarcomas of the inferior vena cava (IVC).
Twenty were treated surgically. Involvement of the IVC included the infrarenal segment …

CyBase: a database of cyclic protein sequences and structures, with applications in protein discovery and engineering

CKL Wang, Q Kaas, L Chiche, DJ Craik - Nucleic acids research, 2007 - academic.oup.com
CyBase was originally developed as a database for backbone-cyclized proteins, providing
search and display capabilities for sequence, structure and function data. Cyclic proteins are …

Retrospective analysis of surgery versus endovascular intervention in Takayasu arteritis: a multicenter experience

…, F Koskas, P Cluzel, C Mignot, Y Schoindre, L Chiche… - Circulation, 2012 - Am Heart Assoc
Background— With recent advances in endovascular treatment, percutaneous endoluminal
angioplasty has become particularly attractive for arterial lesions of Takayasu arteritis. …

Safety and efficacy of immune checkpoint inhibitors in patients with cancer and preexisting autoimmune disease: a nationwide, multicenter cohort study

…, F Brunet‐Possenti, C Stavris, L Chiche… - Arthritis & …, 2019 - Wiley Online Library
Objective Immune checkpoint inhibitors ( ICI s) for cancer therapy frequently induce immune‐related
adverse effects ( IRAE s). Therefore, most patients with preexisting autoimmune …