Juvenile dermatomyositis, the most common inflammatory myopathy of childhood, is a rare
systemic autoimmune vasculopathy that is characterised by weakness in proximal muscles …

Mutations of lamin A/C (LMNA) cause a wide range of human disorders, including progeria,
lipodystrophy, neuropathies and autosomal dominant Emery–Dreifuss muscular dystrophy (…

Objective To estimate the incidence of juvenile dermatomyositis (juvenile DM) in the United
States between 1995 and 1998. Methods Physician referrals to the National Institute of …

Background Most patients with congenital hypogammaglobulinemia and absent B cells are
males with X-linked agammaglobulinemia, which is caused by mutations in the gene for …

… Pachman, MD: Children’s Memorial Hospital and Northwestern University, Chicago, Illinois;
7 … Feldman BM, Rider LG, Reed AM, Pachman LM. Juvenile dermatomyositis and other …

Objective To characterize the association between the TNFα‐308A allele and 1) duration of
active disease, 2) peripheral blood mononuclear cell (PBMC) synthesis of tumor necrosis …

Objective To assess the reliability and validity of the Disease Activity Score (DAS), an instrument
used to evaluate children with juvenile dermatomyositis (JDM). Methods Psychometric …

Objective To develop, validate, and determine the measurement characteristics of a
quantitative tool for assessing the severity of muscle involvement in children with idiopathic …

Juvenile dermatomyositis (JDM), the most common pediatric inflammatory myopathy, is a
systemic vasculopathy affecting young children. Epidemiology studies documenting an …

Objective To evaluate demographic and clinical characteristics, duration of time between
disease onset (date of first rash and/or weakness), and diagnosis/therapy, as well as …