User profiles for LU CHEN

Lu Chen

- Verified email at stanford.edu - Cited by 9298

Lu Chen (陈路)

- Verified email at scu.edu.cn - Cited by 6732

Chen David Lu

- Verified email at mit.edu - Cited by 4319

Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms

L Chen, DM Chetkovich, RS Petralia, NT Sweeney… - Nature, 2000 - nature.com
Stargazer, an ataxic and epileptic mutant mouse, lacks functional AMPA (α-amino-3-hydroxyl-5-methyl-4-isoxazolepropionate)
receptors on cerebellar granule cells. Stargazin, the …

Direct interactions between PSD-95 and stargazin control synaptic AMPA receptor number

…, S Karimzadegan, L Chen… - Proceedings of the …, 2002 - National Acad Sciences
Excitatory synapses in the brain exhibit a remarkable degree of functional plasticity, which
largely reflects changes in the number of synaptic α-amino-3-hydroxy-5-methyl-4-…

[HTML][HTML] A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity

…, X Song, C Chen, Z Xue, S Yao, L Chen, X Ma, S Chen… - Nature, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a respiratory disease
called coronavirus disease 2019 (COVID-19), the spread of which has led to a pandemic. …

The importance of the normality assumption in large public health data sets

…, P Diehr, S Emerson, L Chen - Annual review of public …, 2002 - annualreviews.org
▪ Abstract It is widely but incorrectly believed that the t-test and linear regression are valid
only for Normally distributed outcomes. The t-test and linear regression compare the mean of …

[HTML][HTML] The influence of irrelevant location information on performance: A review of the Simon and spatial Stroop effects

CH Lu, RW Proctor - Psychonomic bulletin & review, 1995 - Springer
The purpose of this paper is to investigate the effect of irrelevant location information on
performance of visual choice-reaction tasks. We review empirical findings and theoretical …

The effect of surface charge on the uptake and biological function of mesoporous silica nanoparticles in 3T3-L1 cells and human mesenchymal stem cells

…, M Yao, CW Lu, YS Lin, Y Hung, CY Mou, YC Chen… - Biomaterials, 2007 - Elsevier
Cellular uptake of nanoparticles for stem cell labeling/tracking is considered as the most
promising method. Recently mesoporous silica nanoparticles (MSNs) are emerging as an idea …

[HTML][HTML] VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment

C Cursiefen, L Chen, LP Borges… - The Journal of …, 2004 - Am Soc Clin Investig
Lymphangiogenesis, an important initial step in tumor metastasis and transplant sensitization,
is mediated by the action of VEGF-C and -D on VEGFR3. In contrast, VEGF-A binds …

[HTML][HTML] Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts

KS Vimaleswaran, DJ Berry, C Lu, E Tikkanen… - PLoS …, 2013 - journals.plos.org
Background Obesity is associated with vitamin D deficiency, and both are areas of active
public health concern. We explored the causality and direction of the relationship between …

An index of substitution saturation and its application

X Xia, Z Xie, M Salemi, L Chen, Y Wang - Molecular phylogenetics and …, 2003 - Elsevier
We introduce a new index to measure substitution saturation in a set of aligned nucleotide
sequences. The index is based on the notion of entropy in information theory. We derive the …

[PDF][PDF] Rapid single-step induction of functional neurons from human pluripotent stem cells

…, C Acuna, J Covy, W Xu, N Yang, T Danko, L Chen… - Neuron, 2013 - cell.com
Available methods for differentiating human embryonic stem cells (ESCs) and induced
pluripotent cells (iPSCs) into neurons are often cumbersome, slow, and variable. Alternatively, …