[HTML][HTML] Loss of health related quality of life following low-trauma fractures in the elderly

…, A Papaioannou, L Bessette, JP Brown, L Pericleous… - BMC geriatrics, 2016 - Springer
Background To estimate the long-term change in health related quality of life (HRQoL)
following low-trauma fractures among individuals receiving home care (HC) services or living in …

[HTML][HTML] Patient-reported utilities in advanced or metastatic melanoma, including analysis of utilities by time to death

AJ Hatswell, B Pennington, L Pericleous… - Health and quality of life …, 2014 - Springer
Background Health-related quality of life is often collected in clinical studies, and forms a
cornerstone of economic evaluation. This study had two objectives, firstly to report and compare …

[HTML][HTML] Abatacept with methotrexate versus other biologic agents in treatment of patients with active rheumatoid arthritis despite methotrexate: a network meta …

P Guyot, P Taylor, R Christensen, L Pericleous… - Arthritis research & …, 2011 - Springer
Introduction The goal of this study was to compare the efficacy in terms of Health Assessment
Questionnaire change from baseline (HAQ CFB), 50% improvement in American College …

Treatment and low-density lipoprotein cholesterol management in patients diagnosed with clinical atherosclerotic cardiovascular disease in Alberta

…, T Cowling, SM Colgan, P Xiang, L Pericleous… - Canadian Journal of …, 2019 - Elsevier
Background Low-density lipoprotein cholesterol (LDL-C) is an important indicator in the
development and management of atherosclerotic cardiovascular disease (ASCVD). Herein, we …

[HTML][HTML] Estimating the impact of delayed access to oncology drugs on patient outcomes in Canada

…, WY Cheung, G Bebb, A Shah, L Pericleous… - Oncology and …, 2022 - Springer
Introduction New requirements in Canada’s pricing processes for patented drugs may
exacerbate delays in regulatory and reimbursement reviews. This study seeks to better …

[HTML][HTML] Increasing prevalence and incidence of atherosclerotic cardiovascular disease in adult patients in Ontario, Canada From 2002 to 2018

…, SG Goodman, RM Rogoza, M Packalen, L Pericleous… - CJC open, 2022 - Elsevier
Background Cardiovascular disease is the second-leading cause of death in Canada. However,
limited data are available on the prevalence of atherosclerotic cardiovascular disease (…

Indirect treatment comparison of abatacept with methotrexate versus other biologic agents for active rheumatoid arthritis despite methotrexate therapy in the United …

…, PC Taylor, R Christensen, L Pericleous… - The Journal of …, 2012 - jrheum.org
Objective. To compare the efficacy of abatacept and alternative biologic disease-modifying
antirheumatic drugs (DMARD) in patients with rheumatoid arthritis (RA) and an inadequate …

The value and consequences of using public health technology assessments for private payer decision-making in Canada: one size does not fit all

L Pericleous, M Amin, R Goeree - Journal of Medical Economics, 2019 - Taylor & Francis
Background: Both public and private insurers provide drug coverage in Canada. All payers
are under pressure to contain costs. It has recently been proposed that private plans …

New View on the Canadian Burden of Stroke: Productivity Loss in Adults Who Return to Work

…, J Mancini, RM Rogoza, L Pericleous - Canadian Journal of …, 2021 - cambridge.org
An often overlooked facet of the indirect costs affecting working-age stroke survivors is the
challenges experienced by those who return to work. This study quantified the productivity …

Burden of Dyslipidaemia in Patients at High Risk for Cardiovascular (Cv) Events: Results of a Canadian Study

D Mitchell, M Habib, L Pericleous… - Value in …, 2015 - valueinhealthjournal.com
Objectives Dyslipidaemia is an important and well recognised modifiable CV risk factor. This
study was undertaken to determine the proportion of patients reaching and maintaining the …