There is emerging evidence that the commensal microbiota has a role in the pathogenesis
of multiple sclerosis (MS), a putative autoimmune disease of the CNS. Here, we compared …

Changes in gut microbiota have been associated with several diseases. Here, the International
Multiple Sclerosis Microbiome Study (iMSMS) studied the gut microbiome of 576 MS …

Objectives: To evaluate the presence of antibodies to conformation-intact myelin oligodendrocyte
glycoprotein (MOG) in a subgroup of adult patients with clinically definite multiple …

We present histological, MRI , and clinical features of an adult patient with relapsing
encephalomyelitis and antibodies against myelin oligodendrocyte glycoprotein ( MOG ). Furthermore…

Objective Autoantibodies against myelin oligodendrocyte glycoprotein (MOG) occur in a
proportion of patients with inflammatory demyelinating diseases of the central nervous system (…

Epstein–Barr virus (EBV) infection precedes multiple sclerosis (MS) pathology and cross-reactive
antibodies might link EBV infection to CNS autoimmunity. As an altered anti-EBV T cell …

Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system
underpinned by partially understood genetic risk factors and environmental triggers and their …

Multiple sclerosis (MS) involves the infiltration of autoreactive T cells into the CNS, yet we lack
a comprehensive understanding of the signaling pathways that regulate this process. Here…

Background The oral sphingosine-1-phosphate receptor modulator fingolimod (FTY720) was
recently approved for the treatment of relapsing-remitting multiple sclerosis. To date, data …

We investigated a patient who developed multiple sclerosis (MS) during treatment with the
CTLA4‐blocking antibody ipilimumab for metastatic melanoma. Initially he showed subclinical …