Randomized controlled trial of vitamin D supplement on endothelial function in patients with type 2 diabetes
…, SW Li, LY Wong, SWL Lee, S Tam, EWK Wong… - Atherosclerosis, 2013 - Elsevier
BACKGROUND: Suboptimal vitamin D status is associated with endothelial dysfunction and
an increased risk of cardiovascular diseases but it is unclear whether vitamin D …
an increased risk of cardiovascular diseases but it is unclear whether vitamin D …
Vitamin D deficiency is associated with depletion of circulating endothelial progenitor cells and endothelial dysfunction in patients with type 2 diabetes
…, LY Wong, SWL Lee, S Tam, EWK Wong… - The Journal of …, 2011 - academic.oup.com
Context: Vitamin D (Vit-D) deficiency is associated with type 2 diabetes mellitus (DM) and
endothelial dysfunction. The relationship of Vit-D deficiency with circulating endothelial …
endothelial dysfunction. The relationship of Vit-D deficiency with circulating endothelial …
[HTML][HTML] Modeling of lamin A/C mutation premature cardiac aging using patient-specific induced pluripotent stem cells
AIMS We identified an autosomal dominant non-sense mutation (R225X) in exon 4 of the
lamin A/C (LMNA) gene in a Chinese family spanning 3 generations with familial dilated …
lamin A/C (LMNA) gene in a Chinese family spanning 3 generations with familial dilated …
Triiodothyronine promotes cardiac differentiation and maturation of embryonic stem cells via the classical genomic pathway
Embryonic stem cells (ESCs) can differentiate into functional cardiomyocytes and thus represent
a promising cell source for cardiac regenerative therapy. Nevertheless, the therapeutic …
a promising cell source for cardiac regenerative therapy. Nevertheless, the therapeutic …
[HTML][HTML] Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese
…, RM Porsch, L Sun, W Xu, H Zheng, LY Wong… - Nature …, 2015 - nature.com
Blood lipids are important risk factors for coronary artery disease (CAD). Here we perform
an exome-wide association study by genotyping 12,685 Chinese, using a custom Illumina …
an exome-wide association study by genotyping 12,685 Chinese, using a custom Illumina …
Modeling treatment response for lamin A/C related dilated cardiomyopathy in human induced pluripotent stem cells
YK Lee, YM Lau, ZJ Cai, WH Lai, LY Wong… - Journal of the …, 2017 - Am Heart Assoc
Background Precision medicine is an emerging approach to disease treatment and prevention
that takes into account individual variability in the environment, lifestyle, and genetic …
that takes into account individual variability in the environment, lifestyle, and genetic …
[HTML][HTML] Attenuation of hind-limb ischemia in mice with endothelial-like cells derived from different sources of human stem cells
Functional endothelial-like cells (EC) have been successfully derived from different cell
sources and potentially used for treatment of cardiovascular diseases; however, their relative …
sources and potentially used for treatment of cardiovascular diseases; however, their relative …
Amelioration of X-linked related autophagy failure in Danon disease with DNA methylation inhibitor
Background: Danon disease is an X-linked disorder that leads to fatal cardiomyopathy caused
by a deficiency in lysosome-associated membrane protein-2 (LAMP2). In female patients, …
by a deficiency in lysosome-associated membrane protein-2 (LAMP2). In female patients, …
Role of circulating endothelial progenitor cells in patients with rheumatoid arthritis with coronary calcification
Objective. Patients with rheumatoid arthritis (RA) are prone to premature atherosclerosis.
We hypothesize that depletion of circulating endothelial progenitor cells (EPC) related to RA …
We hypothesize that depletion of circulating endothelial progenitor cells (EPC) related to RA …
[PDF][PDF] Generation of human liver chimeric mice with hepatocytes from familial hypercholesterolemia induced pluripotent stem cells
Familial hypercholesterolemia (FH) causes elevation of low-density lipoprotein cholesterol (LDL-C)
in blood and carries an increased risk of early-onset cardiovascular disease. A …
in blood and carries an increased risk of early-onset cardiovascular disease. A …