Development of the anti–citrullinated protein antibody repertoire prior to the onset of rheumatoid arthritis

LA van de Stadt, MHMT de Koning… - Arthritis & …, 2011 - Wiley Online Library
… of rheumatoid arthritis - van de Stadt - 2011 - Arthritis & Rheumatism - Wiley Online Library
… LA van de Stadt had full access to all of the data in the study and takes responsibility for the …

Anti-citrullinated protein antibodies acquire a pro-inflammatory Fc glycosylation phenotype prior to the onset of rheumatoid arthritis

Y Rombouts, E Ewing, LA Van De Stadt… - Annals of the …, 2015 - ard.bmj.com
Objective To determine whether anticitrullinated protein antibodies (ACPA) exhibit specific
changes in Fc glycosylation prior to the onset of arthritis. Methods Serum samples of patients …

Brief report: anti–carbamylated protein antibodies are present in arthralgia patients and predict the development of rheumatoid arthritis

J Shi, LA van de Stadt, EWN Levarht… - Arthritis & …, 2013 - Wiley Online Library
van de Stadt Jan van Breemen Research Institute | Reade, Sanquin Research, and Landsteiner
Laboratory, Academic Medical Center, … van de Stadt contributed equally to this work. …

Anti-carbamylated protein (anti-CarP) antibodies precede the onset of rheumatoid arthritis

J Shi, LA van de Stadt, EWN Levarht… - Annals of the …, 2014 - ard.bmj.com
Objective The presence of anti-citrullinated protein antibodies (ACPA) and IgM-rheumatoid
factor (IgM-RF) years before the clinical diagnosis of rheumatoid arthritis (RA) suggests they …

A prediction rule for the development of arthritis in seropositive arthralgia patients

LA Van De Stadt, BI Witte, WH Bos… - Annals of the …, 2013 - ard.bmj.com
… protein (hsCRP) was measured using a highly sensitive latex-enhanced assay on a Hitachi
911 analyser (Roche Diagnostics) and the cut-off level for CRP positivity was set at 10 mg/l, …

Adalimumab elicits a restricted anti-idiotypic antibody response in autoimmune patients resulting in functional neutralisation

PA van Schouwenburg, LA van de Stadt… - Annals of the …, 2013 - ard.bmj.com
Objectives Millions of patients worldwide are treated with therapeutic monoclonal antibodies.
These biological therapeutics can be immunogenic, resulting in anti-drug antibody …

The extent of the anti-citrullinated protein antibody repertoire is associated with arthritis development in patients with seropositive arthralgia

LA van de Stadt, AR van der Horst… - Annals of the …, 2011 - ard.bmj.com
Objectives To determine the fine specificity of anti-citrullinated protein antibodies (ACPA) in
the early phase of arthritis development, the ACPA repertoire in arthralgia patients and the …

The type I IFN signature as a biomarker of preclinical rheumatoid arthritis

J Lübbers, M Brink, LA van de Stadt… - Annals of the …, 2013 - ard.bmj.com
Objectives To validate the presence and demonstrate the clinical value of the type I interferon
(IFN)-signature during arthritis development. Method In 115 seropositive arthralgia patients …

[HTML][HTML] The value of ultrasonography in predicting arthritis in auto-antibody positive arthralgia patients: a prospective cohort study

LA van de Stadt, WH Bos… - Arthritis research & …, 2010 - Springer
Introduction Ultrasonography (US) has better sensitivity than clinical evaluation for the detection
of synovitis in early rheumatoid arthritis (RA). Patients presenting with arthralgia and a …

Avidity maturation of anti–citrullinated protein antibodies in rheumatoid arthritis

P Suwannalai, LA Van De Stadt, H Radner… - Arthritis & …, 2012 - Wiley Online Library
… Suwannalai and van de Stadt contributed equally to this work… Suwannalai and van de Stadt
contributed equally to this work… Suwannalai and van de Stadt contributed equally to this work. …