The current economic burden of illness of osteoporosis in Canada

…, L Bessette, JP Brown, L Pericleous… - Osteoporosis …, 2016 - Springer
We estimate the current burden of illness of osteoporosis in Canada is double ($4.6 billion)
our previous estimates ($2.3 billion) due to improved data capture of the multiple encounters …

[HTML][HTML] Abatacept with methotrexate versus other biologic agents in treatment of patients with active rheumatoid arthritis despite methotrexate: a network meta …

P Guyot, P Taylor, R Christensen, L Pericleous… - Arthritis research & …, 2011 - Springer
Introduction The goal of this study was to compare the efficacy in terms of Health Assessment
Questionnaire change from baseline (HAQ CFB), 50% improvement in American College …

[HTML][HTML] Loss of health related quality of life following low-trauma fractures in the elderly

…, A Papaioannou, L Bessette, JP Brown, L Pericleous… - BMC geriatrics, 2016 - Springer
Background To estimate the long-term change in health related quality of life (HRQoL)
following low-trauma fractures among individuals receiving home care (HC) services or living in …

The burden and management of FXIII deficiency

T De Jager, L Pericleous, M Kokot‐Kierepa… - …, 2014 - Wiley Online Library
Factor XIII congenital deficiency ( FXIII CD ) is a serious bleeding disorder resulting in a
lifelong bleeding tendency, defective wound healing and recurrent miscarriage. The aim of this …

[HTML][HTML] Patient-reported utilities in advanced or metastatic melanoma, including analysis of utilities by time to death

AJ Hatswell, B Pennington, L Pericleous… - Health and quality of life …, 2014 - Springer
Background Health-related quality of life is often collected in clinical studies, and forms a
cornerstone of economic evaluation. This study had two objectives, firstly to report and compare …

Indirect treatment comparison of abatacept with methotrexate versus other biologic agents for active rheumatoid arthritis despite methotrexate therapy in the United …

…, PC Taylor, R Christensen, L Pericleous… - The Journal of …, 2012 - jrheum.org
Objective. To compare the efficacy of abatacept and alternative biologic disease-modifying
antirheumatic drugs (DMARD) in patients with rheumatoid arthritis (RA) and an inadequate …

Treatment and low-density lipoprotein cholesterol management in patients diagnosed with clinical atherosclerotic cardiovascular disease in Alberta

…, T Cowling, SM Colgan, P Xiang, L Pericleous… - Canadian Journal of …, 2019 - Elsevier
… Par la présente, nous décrivons la prise en charge du cholestérol LDL à l’aide d’un
traitement hypolipémiant chez les patients de l’Alberta, au Canada, qui ont reçu un diagnostic …

[HTML][HTML] Estimating the impact of delayed access to oncology drugs on patient outcomes in Canada

…, WY Cheung, G Bebb, A Shah, L Pericleous… - Oncology and …, 2022 - Springer
Introduction New requirements in Canada’s pricing processes for patented drugs may
exacerbate delays in regulatory and reimbursement reviews. This study seeks to better …

[HTML][HTML] Characterisation and internalisation of recombinant humanised HMFG-1 antibodies against MUC1

LM Pericleous, J Richards, AA Epenetos… - British journal of …, 2005 - nature.com
The humanised HMFG-1 immunoglobulin has been extensively developed as a clinical
immunotherapeutic agent for MUC1 expressing tumours. We have constructed a single-chain Fv …

[HTML][HTML] Increasing prevalence and incidence of atherosclerotic cardiovascular disease in adult patients in Ontario, Canada From 2002 to 2018

…, SG Goodman, RM Rogoza, M Packalen, L Pericleous… - CJC open, 2022 - Elsevier
… sur l’incidence et la prévalence de la MCVAS chez les adultes ontariens consignées dans le
référentiel de l’… de la manifestation index et de l’intervention; caractéristiques des patients et …