Little is known about the pathophysiology of pelvic organ prolapse (POP). In 1996, Jackson
presented a hypothesis on pelvic floor connective tissue that tried to explain the …

A positional cloning approach has led to the identification of two closely related genes, the
presenilins (PS), for autosomal dominant presenile Alzheimer disease (AD): PS-1 at 14q24.3 …

Therapeutic strategies harnessing the immune system to eliminate tumour cells have been
successfully used for several cancer types, including in patients with advanced-stage non-…

… any oral or intravenous corticosteroids on the day PD-(L)1 blockade was started. Use of
corticosteroids within 30 days of the start of PD-(L)1 blockade was also collected for the MSKCC …

Several families with an early–onset form of familial Alzheimer's disease have been found to
harbour mutations at a specific codon (717) of the gene for the β–amyloid precursor protein (…

Background First-line durvalumab plus etoposide with either cisplatin or carboplatin (platinum–etoposide)
showed a significant improvement in overall survival versus platinum–…

The advent of chemical biology tools for imaging and tracking of biomolecules (proteins,
lipids, glycans) in their native environment is providing unique insights into cellular processes …

… l FDA approved; not EMA approved. m A parallel ESMO CPG on non-oncogene-addicted
mNSCLC is available at: https://www.esmo.org/guidelines/guidelines-by-topic/lung-and-chest-…

Small-cell lung cancer (SCLC) is the most aggressive form of lung cancer. Although SCLC
is characterised by rapid responses to chemotherapy (ChT) and sensitivity to radiotherapy (RT…

The set of 270 different srRNA sequences listed in Table 1 comprises complete sequences
and continuous partial sequences, but no discontinuous partial sequences. In order to limit …