The objective of this systematic literature review was to determine the association between
cardiovascular events (CVEs) and antirheumatic drugs in rheumatoid arthritis (RA) and …

Objective. Comorbidities such as cardiovascular diseases (CVD), cancer, osteoporosis, and
depression are often underrecognized in patients with rheumatoid arthritis (RA), psoriatic …

Background Twenty to fifty percent of patients with psoriasis have depressive symptoms.
Objective To describe the effects of biologics (tumour necrosis factor inhibitors [ TNF i] or …

Objective To compare the efficacy of a single intraarticular corticosteroid injection, a
supervised physiotherapy program, a combination of the two, and placebo in the treatment of …

Importance Nonrandomized studies using insurance claims databases can be analyzed to
produce real-world evidence on the effectiveness of medical products. Given the lack of …

Background Upadacitinib is a selective inhibitor of Janus kinase 1 and was efficacious in
phase 2 studies in patients with moderate-to-severe rheumatoid arthritis. We aimed to assess …

Objective To evaluate the efficacy, including capacity for inhibition of radiographic
progression, and safety of upadacitinib, a JAK 1‐selective inhibitor, as compared to placebo or …

… Additional pre-specified secondary outcomes reported are the change from baseline in
CRP (mg/L) and change from baseline in MRI SPARCC sacroiliac joint score. Other secondary …

Objective To evaluate the efficacy and safety of ustekinumab in 3 randomized, placebo‐controlled
studies in patients with axial spondyloarthritis (SpA). Studies 1 and 2 included patients …

Objective To determine the effect of chondroitin sulphate (CS) treatment on cartilage volume
loss, subchondral bone marrow lesions (BML), synovitis and disease symptoms in patients …