CD100 is a leukocyte semaphorin
…, A Elhabazi, A Bensussan, L Boumsell - Cellular and Molecular …, 1998 - Springer
CD100 was originally described as an activation molecule on the surface of human T
lymphocytes. Its triggering through distinct epitopes leads to different signals of costimulation with …
lymphocytes. Its triggering through distinct epitopes leads to different signals of costimulation with …
Toxic epidermal necrolysis: effector cells are drug-specific cytotoxic T cells
A Nassif, A Bensussan, L Boumsell, A Deniaud… - Journal of allergy and …, 2004 - Elsevier
BACKGROUND: Toxic epidermal necrolysis (TEN) is a very rare but extremely severe drug
reaction characterized by widespread apoptosis of epidermis with extensive blisters. We …
reaction characterized by widespread apoptosis of epidermis with extensive blisters. We …
Human CD100, a novel leukocyte semaphorin that promotes B-cell aggregation and differentiation.
KT Hall, L Boumsell, JL Schultze… - Proceedings of the …, 1996 - National Acad Sciences
Herein we describe the molecular characterization of the human leukocyte activation antigen
CD100 and identify it as the first semaphorin, to our knowledge, in the immune system. …
CD100 and identify it as the first semaphorin, to our knowledge, in the immune system. …
[HTML][HTML] Drug specific cytotoxic T-cells in the skin lesions of a patient with toxic epidermal necrolysis
…, A Bensussan, N Bachot, M Bagot, L Boumsell… - Journal of Investigative …, 2002 - Elsevier
Toxic epidermal necrolysis is an extremely severe drug reaction, manifesting itself by
widespread apoptosis of keratinocytes, generally considered to result from Fas/CD95–FasLigand …
widespread apoptosis of keratinocytes, generally considered to result from Fas/CD95–FasLigand …
CD38 and CD100 lead a network of surface receptors relaying positive signals for B-CLL growth and survival
…, L Bonello, AL Horenstein, L Tamagnone, L Boumsell… - Blood, 2005 - ashpublications.org
This work addresses the question whether CD38, a negative prognostic marker in B-cell
chronic lymphocytic leukemia (B-CLL), plays a role in neoplastic B-cell growth and survival. We …
chronic lymphocytic leukemia (B-CLL), plays a role in neoplastic B-cell growth and survival. We …
[HTML][HTML] Evaluation of the potential role of cytokines in toxic epidermal necrolysis
…, M Bagot, L Lyonnet, L Michel, L Boumsell… - Journal of Investigative …, 2004 - Elsevier
… (TNF-α, sFas-L, IL-10) rather originated from activated keratinocytes. Fas-L was indeed …
We propose the hypothesis that the production of Fas-L, TNF-α, and IL-10 by keratinocytes …
We propose the hypothesis that the production of Fas-L, TNF-α, and IL-10 by keratinocytes …
Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury
…, M Cieslak, R Fan, L Boumsell… - Proceedings of the …, 2007 - National Acad Sciences
Semaphorin 4D (sema4D; CD100) is an integral membrane protein and the ligand for two
receptors, CD72 and plexin-B1. Soluble sema4D has been shown to evoke angiogenic …
receptors, CD72 and plexin-B1. Soluble sema4D has been shown to evoke angiogenic …
Blister fluid T lymphocytes during toxic epidermal necrolysis are functional cytotoxic cells which express human natural killer (NK) inhibitory receptors
L Le Cleach, S Delaire, L Boumsell… - Clinical & …, 2000 - academic.oup.com
Toxic epidermal necrolysis (TEN) is a rare life-threatening adverse drug reaction characterized
by a massive destruction of the epidermis. Immunohistological studies of skin biopsies of …
by a massive destruction of the epidermis. Immunohistological studies of skin biopsies of …
Biological activity of soluble CD100. II. Soluble CD100, similarly to H-SemaIII, inhibits immune cell migration
…, A Elhabazi, A Bensussan, L Boumsell - The Journal of …, 2001 - journals.aai.org
CD100 is a human 150-kDa homodimer expressed at the surface of most hemopoietic cells,
and its gene belongs to the Ig and semaphorin gene families. Semaphorin genes encode …
and its gene belongs to the Ig and semaphorin gene families. Semaphorin genes encode …
CD molecules 2006—human cell differentiation molecules
…, S Barry, A Beare, A Bensussan, L Boumsell… - Journal of …, 2007 - Elsevier
The Human Leucocyte Differentiation Antigens Workshops (HLDA) have since 1984 provided
a forum for the characterization and study of leucocyte surface molecules and antibodies …
a forum for the characterization and study of leucocyte surface molecules and antibodies …