Total daily energy expenditure (“total expenditure”) reflects daily energy needs and is a
critical variable in human health and physiology, but its trajectory over the life course is poorly …

Background Although stroke is the second leading cause of death worldwide, no
comprehensive and comparable assessment of incidence, prevalence, mortality, disability, and …

Background Coronary heart disease (CHD) is the single most common cause of death globally.
However, with falling CHD mortality rates, an increasing number of people live with CHD …

Background The burden of ischaemic and haemorrhagic stroke varies between regions and
over time. With differences in prognosis, prevalence of risk factors, and treatment strategies, …

Formalised knowledge systems, including universities and research institutes, are important
for contemporary societies. They are, however, also arguably failing humanity when their …

Background A worldwide outbreak of severe acute respiratory syndrome (SARS) has been
associated with exposures originating from a single ill health care worker from Guangdong …

We present a one per cent measurement of the cosmic distance scale from the detections of
the baryon acoustic oscillations (BAO) in the clustering of galaxies from the Baryon …

In March 2003, a novel coronavirus (SARS-CoV) was discovered in association with cases
of severe acute respiratorysyndrome (SARS). The sequence of the complete genome of …

Background Reliable and timely information on the leading causes of death in populations,
and how these are changing, is a crucial input into health policy debates. In the Global …

Background Measuring disease and injury burden in populations requires a composite metric
that captures both premature mortality and the prevalence and severity of ill-health. The …