[HTML][HTML] Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-κB activation and protection from cell death

K Tada, T Okazaki, S Sakon, T Kobarai… - Journal of Biological …, 2001 - ASBMB
Tumor necrosis factor (TNF) receptor-associated factors (TRAFs) were identified as signal
transducers for the TNF receptor superfamily. However, the exact roles of TRAF2 and TRAF5 …

Ixekizumab, an interleukin-17A antagonist in the treatment of ankylosing spondylitis or radiographic axial spondyloarthritis in patients previously untreated with …

…, M Malcova, Y Taniguchi, M Kishimoto, K Tada… - The Lancet, 2018 - thelancet.com
Background Biological disease-modifying anti-rheumatic drugs (bDMARDs) are recommended
for radiographic axial spondyloarthritis, otherwise known as ankylosing spondylitis, when …

Ixekizumab for patients with non-radiographic axial spondyloarthritis (COAST-X): a randomised, placebo-controlled trial

…, L Paimela, Y Taniguchi, T Tsuda, K Tada… - The Lancet, 2020 - thelancet.com
Background Ixekizumab, a high-affinity interleukin-17A (IL-17A) monoclonal antibody, has
previously shown efficacy in radiographic axial spondyloarthritis (also known as ankylosing …

Targeted disruption of Traf5 gene causes defects in CD40- and CD27-mediated lymphocyte activation

…, H Koseki, T Takemori, K Tada… - Proceedings of the …, 1999 - National Acad Sciences
TRAF5 [tumor necrosis factor (TNF) receptor-associated factor 5] is implicated in NF-κB and
c-Jun NH 2 -terminal kinase/stress-activated protein kinase activation by members of the …

[HTML][HTML] Expanding the spectrum of reactive arthritis (ReA): classic ReA and infection-related arthritis including poststreptococcal ReA, Poncet's disease, and iBCG …

…, H Nishikawa, T Yoshida, Y Terada, K Tada… - Rheumatology …, 2021 - Springer
Reactive arthritis (ReA) is a form of sterile arthritis that occurs secondary to an extra-articular
infection in genetically predisposed individuals. The extra-articular infection is typically an …

Clinical characteristics and change in the antibody titres of patients with anti-MDA5 antibody–positive inflammatory myositis

Y Abe, M Matsushita, K Tada, K Yamaji… - …, 2017 - academic.oup.com
Objective The aim of this study was to evaluate the clinical characteristics of patients with
anti-melanoma differentiation–associated gene 5 (MDA5) antibody–positive inflammatory …

Involvement of mucosal-associated invariant T cells in ankylosing spondylitis

E Hayashi, A Chiba, K Tada, K Haga… - The Journal of …, 2016 - jrheum.org
Objective. Ankylosing spondylitis (AS) is characterized by chronic inflammation of the axial
and peripheral joints and ligamentous attachments. Gut immunity is thought to be involved in …

Successful treatment of anti-MDA5 antibody-positive refractory interstitial lung disease with plasma exchange therapy

Y Abe, M Kusaoi, K Tada, K Yamaji, N Tamura - Rheumatology, 2020 - academic.oup.com
Objectives We examined the effectiveness of plasma exchange (PE) therapy to reduce the
mortality of rapidly progressive interstitial lung disease (RP-ILD) in patients positive for anti-…

Non-radiographic axial spondyloarthritis

…, N Tamura, Y Kadono, K Tada… - Modern …, 2021 - academic.oup.com
Kurisu Tada , Kurisu Tada … Hideto Kameda, Shigeto Kobayashi, Naoto Tamura, Yuho
Kadono, Kurisu Tada, Masahiro Yamamura, Tetsuya Tomita, Non-radiographic axial …

Predictive grade of ultrasound synovitis for diagnosing rheumatoid arthritis in clinical practice and the possible difference between patients with and without …

…, N Sugisaki, S Ando, T Kon, K Tada… - Modern …, 2016 - academic.oup.com
Objective. To determine the degree of contribution and the contributing factors of ultrasound
in the diagnosis of rheumatoid arthritis (RA) in daily clinical practice and the predictive …