p130 Cas (Cas) has been recently identified as a 130-kDa protein that is highly phosphorylated
on tyrosine residues and is stably associated with p47 v-crk (v-Crk) and p60 v-src (v-Src) …

… Author links open overlay panel Hiroko Kanda , Kanae Kubo , Ken Hamasaki , Yoshinobu
Kanda MD , Akihide Nakao , Tadaichi Kitamura , Toshiro Fujita , Kazuhiko Yamamoto , …

Cell adhesion to extracellular matrix proteins is a dynamic process leading to dramatic
changes in the cell phenotype. Integrins are one of the major receptor families that mediate cell-…

A novel signaling molecule p130 Cas has been shown to undergo tyrosine phosphorylation
in response to integrin-mediated cell adhesion. In this study, we have attempted to identify …

The characteristics of Pneumocystis carinii pneumonia (PCP) in patients with connective tissue
diseases (CTDs) were examined retrospectively. Nine patients were enrolled in this study…

Autoantibodies against proliferating cell nuclear antigen (PCNA) have been detected almost
exclusively in sera from patients with systemic lupus erythematosus (SLE). Because of the …

Mechanical loading of cultured mesangial cells has been shown to induce both increased
production of matrix proteins and cell proliferation. This in vitro phenomenon has been …

Sarcoidosis is a chronic multisystem disease of unknown etiology characterized by
noncaseating granulomatous inflammation. Sarcoidosis sometimes accompanies autoimmune …

p105 CasL (CasL) is a recently identified signaling molecule closely related to the p130 Cas
(Crk‐associated substrate) docking protein. CasL has a single Src homology (SH) 3 domain …

MRL/Mp-lpr/lpr (lpr) mice develop autoantibodies, vasculitis, and glomerulonephritis, which
are similar to human systemic lupus erythematosus, and acquire a generalized, …