User profiles for KEVIN D. DEANE

Kevin D. Deane

Verified email at cuanschutz.edu
Cited by 11503

2021 American College of Rheumatology guideline for the treatment of rheumatoid arthritis

…, T Arayssi, K Carandang, KD Deane… - Arthritis & …, 2021 - Wiley Online Library
Objective To develop updated guidelines for the pharmacologic management of rheumatoid
arthritis. Methods We developed clinically relevant population, intervention, comparator, …

Global epidemiology of rheumatoid arthritis

…, R Thomas, KD Deane, D Alpizar-Rodriguez… - Nature Reviews …, 2022 - nature.com
Rheumatoid arthritis (RA) is a systemic autoimmune disease that predominantly affects the
joints. The prevalence of RA varies globally, with generally a higher prevalence in …

Genetic and environmental risk factors for rheumatoid arthritis

KD Deane, MK Demoruelle, LB Kelmenson… - Best practice & research …, 2017 - Elsevier
Multiple genetic and environmental factors have been associated with an increased risk for
rheumatoid arthritis (RA). Of these, the strongest associations have been seen with female …

[HTML][HTML] Autoantibody epitope spreading in the pre-clinical phase predicts progression to rheumatoid arthritis

J Sokolove, R Bromberg, KD Deane, LJ Lahey… - PloS one, 2012 - journals.plos.org
Rheumatoid arthritis (RA) is a prototypical autoimmune arthritis affecting nearly 1% of the
world population and is a significant cause of worldwide disability. Though prior studies have …

Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum

…, DN Frank, MK Demoruelle, KD Deane… - Science translational …, 2022 - science.org
The mucosal origins hypothesis of rheumatoid arthritis (RA) proposes a central role for
mucosal immune responses in the initiation or perpetuation of the systemic autoimmunity that …

Brief Report: Airways abnormalities and rheumatoid arthritis–related autoantibodies in subjects without arthritis: Early injury or initiating site of autoimmunity?

…, JM Norris, VM Holers, KD Deane - Arthritis & …, 2012 - Wiley Online Library
Objective To evaluate the presence of pulmonary abnormalities in rheumatoid arthritis (RA)–related
autoantibody–positive subjects without inflammatory arthritis. Methods Forty‐two …

Endothelial function is impaired across the stages of the menopause transition in healthy women

…, KL Hildreth, AL Meditz, KD Deane… - The Journal of …, 2012 - academic.oup.com
Context: The stages of the menopause transition are characterized by changes in ovarian
hormones and increased cardiovascular disease (CVD) risk factors and vasomotor symptoms …

The number of elevated cytokines and chemokines in preclinical seropositive rheumatoid arthritis predicts time to diagnosis in an age‐dependent manner

KD Deane, CI O'Donnell, W Hueber… - Arthritis & …, 2010 - Wiley Online Library
Objective To evaluate levels of biomarkers in preclinical rheumatoid arthritis (RA) and to
use elevated biomarkers to develop a model for the prediction of time to future diagnosis of …

Porphyromonas gingivalis and disease‐related autoantibodies in individuals at increased risk of rheumatoid arthritis

TR Mikuls, GM Thiele, KD Deane… - Arthritis & …, 2012 - Wiley Online Library
Objective To examine the relationship of Porphyromonas gingivalis to the presence of
autoantibodies in individuals at risk of rheumatoid arthritis (RA). Methods Study participants …

Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to destruction

…, Y Okamoto, JM Norris, KD Deane - Nature Reviews …, 2018 - nature.com
Individuals at high risk of developing seropositive rheumatoid arthritis (RA) can be identified
for translational research and disease prevention studies through the presence of highly …