Obstructive sleep apnea (OSA) is characterized by repeated occurrences of hypoxic,
hypercapnic, and transient blood pressure elevation episodes that may damage or alter neural …

We present a technique for removing global effects from functional magnetic resonance
imaging (fMRI) images, using a voxel-level linear model of the global signal (LMGS). The …

Background Valganciclovir is an orally administered prodrug that is rapidly hydrolyzed to
ganciclovir. We compared the effects of oral valganciclovir with those of intravenous ganciclovir …

Objective. To evaluate the longterm safety of rituximab in clinical trials in patients with
rheumatoid arthritis (RA). Methods. Pooled analysis of safety data, including adverse events (AE) …

We investigated the emergence of cytomegalovirus (CMV) ganciclovir-resistance mutations
in 301 high-risk solid-organ transplant (SOT) recipients after oral prophylaxis, for 100 days, …

Obstructive sleep apnea (OSA) patients exhibit altered sympathetic outflow, which may reveal
mechanisms underlying the syndrome. We used functional MRI (fMRI) in 16 control and 10 …

The Valsalva maneuver, a test frequently used to evaluate autonomic function, recruits
discrete neural sites. The time courses of neural recruitment relative to accompanying …

Congenital central hypoventilation syndrome (CCHS) patients show deficient respiratory
and cardiac responses to hypoxia and hypercapnia, despite apparently intact arousal …

Congenital central hypoventilation syndrome (CCHS) patients show impaired ventilatory
responses and loss of breathlessness to hypercapnia, yet arouse from sleep to high CO 2 , …

The repetitive upper airway muscle atonic episodes and cardiovascular sequelae of obstructive
sleep apnea (OSA) suggest dysfunction of specific neural sites that integrate afferent …