Rationale: Coronavirus disease 2019 (COVID-19) is characterized by increased incidence of
microthrombosis with hyperactive platelets sporadically containing viral RNA. It is unclear if …

Objective: Inflammatory activity in fat tissue has recently been implicated in mechanisms of
insulin resistance and obesity‐related metabolic dysfunction. Toll‐like receptors (TLRs) play …

Cells of the innate immune system use Toll-like receptors (TLRs) to initiate the proinflammatory
response to microbial infection. Recent studies have shown acute infections are …

There is growing appreciation for the importance of non-protein-coding genes in development
and disease. Although much is known about microRNAs, limitations in bioinformatic …

The Extracellular RNA Communication Consortium (ERCC) was launched to accelerate
progress in the new field of extracellular RNA (exRNA) biology and to establish whether …

Background Identification of single nucleotide polymorphisms (SNPs) associated with gene
expression levels, known as expression quantitative trait loci (eQTLs), may improve …

Objective— Interleukin 1 Receptor 1 (IL1R1) and its ligand, IL1β, are upregulated in
cardiovascular disease, obesity, and infection. Previously, we reported a higher level of IL1R1 …

Identification of microRNA expression quantitative trait loci (miR-eQTL) can yield insights
into regulatory mechanisms of microRNA transcription, and can help elucidate the role of …

Objective— Soluble CD40 ligand (sCD40L) has been recently implicated in the pathogenesis
of atherosclerosis. Elevated levels of sCD40L in acute coronary syndrome patients …

Recent studies provide evidence of correlations of DNA methylation and expression of
protein‐coding genes with human aging. The relations of micro RNA expression with age and age…