User profiles for K. WONG

Kwong-Kwok Wong

Professor, Department of Gynecologic Oncology and Reprod Med, UT MD Anderson Cancer …
Verified email at mdanderson.org
Cited by 10706

Recent developments in anti-cancer agents targeting the Ras/Raf/MEK/ERK pathway

KK Wong - Recent patents on anti-cancer drug discovery, 2009 - ingentaconnect.com
The Ras/Raf/MEK/ERK mitogen-activated protein kinase (MAPK) pathway mediates cellular
responses to different growth signals and is frequently deregulated in cancer. There are …

Traditional Chinese herbal medicines for treatment of liver fibrosis and cancer: from laboratory discovery to clinical evaluation

JM Luk, X Wang, P Liu, KF Wong, KL Chan… - Liver …, 2007 - Wiley Online Library
Liver disease afflicts over 10% of the world population. This includes chronic hepatitis,
alcoholic steatosis, fibrosis, cirrhosis and hepatocellular carcinoma (HCC), which are the most …

Tripterygium wilfordii bioactive compounds as anticancer and anti-inflammatory agents.

KF Wong, Y Yuan, JM Luk - Clinical & Experimental …, 2012 - search.ebscohost.com
Bioactive compounds from medicinal plants with anticancer and anti-inflammatory effects
have become key resources in drug discovery fields for the treatment of various malignancies …

Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma

…, C Tennakoon, FH Mulawadi, KF Wong… - Nature …, 2012 - nature.com
To survey hepatitis B virus (HBV) integration in liver cancer genomes, we conducted massively
parallel sequencing of 81 HBV-positive and 7 HBV-negative hepatocellular carcinomas (…

[HTML][HTML] Exosomal transfer of stroma-derived miR21 confers paclitaxel resistance in ovarian cancer cells through targeting APAF1

…, CS Leung, Y Li, ES Lu, K Kwan, KK Wong… - Nature …, 2016 - nature.com
Advanced ovarian cancer usually spreads to the visceral adipose tissue of the omentum.
However, the omental stromal cell-derived molecular determinants that modulate ovarian …

Osteopontin as a potential diagnostic biomarker for ovarian cancer

JH Kim, SJ Skates, T Uede, K Wong, JO Schorge… - Jama, 2002 - jamanetwork.com
ContextDevelopment of new biomarkers for ovarian cancer is needed for early detection and
disease monitoring. Analyses involving complementary DNA (cDNA) microarray data can …

Functional abnormalities in patients with permanent right ventricular pacing: the effect of sites of electrical stimulation

HF Tse, C Yu, KK Wong, V Tsang, YL Leung… - Journal of the American …, 2002 - jacc.org
Objectives : We sought to evaluate the long-term effects of alternative right ventricular
pacing sites on myocardial function and perfusion. Background : Previous studies have …

Global analysis of the Deinococcus radiodurans proteome by using accurate mass tags

…, A Venkateswaran, KK Wong… - Proceedings of the …, 2002 - National Acad Sciences
Understanding biological systems and the roles of their constituents is facilitated by the ability
to make quantitative, sensitive, and comprehensive measurements of how their proteome …

TGF-β modulates ovarian cancer invasion by upregulating CAF-derived versican in the tumor microenvironment

TL Yeung, CS Leung, KK Wong, G Samimi… - Cancer research, 2013 - AACR
TGF-β has limited effects on ovarian cancer cells, but its contributions to ovarian tumor growth
might be mediated through elements of the tumor microenvironment. In the present study, …

[HTML][HTML] Identification of a novel salt tolerance gene in wild soybean by whole-genome sequencing

…, Y Tao, FL Wong, S Isobe, CF Wong, KS Wong… - Nature …, 2014 - nature.com
Using a whole-genome-sequencing approach to explore germplasm resources can serve as
an important strategy for crop improvement, especially in investigating wild accessions that …