[HTML][HTML] Induction of pluripotent stem cells from adult human fibroblasts by defined factors
K Takahashi, K Tanabe, M Ohnuki, M Narita, T Ichisaka… - cell, 2007 - cell.com
Successful reprogramming of differentiated human somatic cells into a pluripotent state
would allow creation of patient- and disease-specific stem cells. We previously reported …
would allow creation of patient- and disease-specific stem cells. We previously reported …
[HTML][HTML] The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
…, H Itoh, K Segawa, M Murakami, K Takahashi… - Cell, 2003 - cell.com
Embryonic stem (ES) cells derived from the inner cell mass (ICM) of blastocysts grow
infinitely while maintaining pluripotency. Leukemia inhibitory factor (LIF) can maintain self-renewal …
infinitely while maintaining pluripotency. Leukemia inhibitory factor (LIF) can maintain self-renewal …
[HTML][HTML] The Shared Socioeconomic Pathways and their energy, land use, and greenhouse gas emissions implications: An overview
This paper presents the overview of the Shared Socioeconomic Pathways (SSPs) and their
energy, land use, and emissions implications. The SSPs are part of a new scenario …
energy, land use, and emissions implications. The SSPs are part of a new scenario …
Favipiravir (T-705), a novel viral RNA polymerase inhibitor
… The IC 50 for the human RNA polymerase II was 905 μM (Takahashi et al., 2011); favipiravir
was therefore 2650 times more selective for the influenza virus RdRP, consistent with the …
was therefore 2650 times more selective for the influenza virus RdRP, consistent with the …
[HTML][HTML] Oxford classification of IgA nephropathy 2016: an update from the IgA nephropathy classification working group
Since the Oxford Classification of IgA nephropathy (IgAN) was published in 2009, MEST
scores have been increasingly used in clinical practice. Further retrospective cohort studies …
scores have been increasingly used in clinical practice. Further retrospective cohort studies …
[HTML][HTML] Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
K Takahashi, S Yamanaka - cell, 2006 - cell.com
… In addition, we examined Fbx15 βgeo/βgeo MEFs in which the four factors had been
introduced without G418 selection, immortalized MEFs expressing K-RasV12, and NIH 3T3 cells …
introduced without G418 selection, immortalized MEFs expressing K-RasV12, and NIH 3T3 cells …
Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 32 cancer groups, 1990 to …
…, J Stanaway, C Steiner, J Sun, K Takahashi… - JAMA …, 2017 - jamanetwork.com
Importance Cancer is the second leading cause of death worldwide. Current estimates on
the burden of cancer are needed for cancer control planning. Objective To estimate mortality, …
the burden of cancer are needed for cancer control planning. Objective To estimate mortality, …
Welcome to the Tidyverse
…, K Takahashi, D Vaughan, C Wilke, K Woo… - Journal of open source …, 2019 - joss.theoj.org
At a high level, the tidyverse is a language for solving data science challenges with R code.
Its primary goal is to facilitate a conversation between a human and a computer about data. …
Its primary goal is to facilitate a conversation between a human and a computer about data. …
The global burden of cancer 2013
Importance Cancer is among the leading causes of death worldwide. Current estimates of
cancer burden in individual countries and regions are necessary to inform local cancer control …
cancer burden in individual countries and regions are necessary to inform local cancer control …
The JRA-55 reanalysis: General specifications and basic characteristics
…, H Endo, K Miyaoka, K Takahashi - Journal of the …, 2015 - jstage.jst.go.jp
… Thresholds (H, V) should be 0 K for ideal snow but in practice need to be adjusted depending
on the snow and surface condition. Accordingly, those values were determined for each …
on the snow and surface condition. Accordingly, those values were determined for each …