There has been a marked increase in the past 15 years in the number and quality of clinical
trials in the idiopathic inflammatory vasculitides, especially the small-vessel vasculitides …

Giant cell (GCA) and Takayasu’s arteritis (TAK) are 2 forms of large-vessel vasculitis (LVV)
that involve the aorta and its major branches. GCA has a predilection for the cranial branches, …

Objective To document disease activity and functional status in patients with scleroderma (systemic
sclerosis [SSc]) and Raynaud's phenomenon (RP) and to determine the sensitivity to …

Objective To register all newly diagnosed patients with primary systemic vasculitides (PSV)
in a large region in northern Germany. Methods Between January 1, 1998 and December 31, …

Objective First, to investigate the overall efficacy and safety of rituximab (RTX) in refractory
granulomatosis with polyangiitis (GPA) in a tertiary referral centre. Second, to compare the …

Aims The quantitative assessment of disease extent (staging) and activity (grading) in patients
with ANCA-associated vasculitides is one prerequisite for the comparison of outcomes in …

… K Herlyn1, … K Holl-Ulrich2, … Klein U, Goossens T, Fischer M, Kanzler H, Braeuninger A,
Rajewsky K, et al. Somatic hypermutation in normal and transformed human B cells. Immunol Rev…

Objectives. The aim of this study was to investigate the period prevalences of ANCA-associated
vasculitides (AAV), including granulomatosis with polyangiitis (GPA), microscopic …

… E-mail: karen.herlyn@uk-sh.de. Submitted for publication January 8, 2010; accepted in …
De Groot K, Gross WL, Herlyn K, Reinhold-Keller E. Development and validation of a disease …

Objective To examine the long‐term efficacy of low‐dose intravenous methotrexate (MTX)
with and without concomitant glucocorticoids (GC) for remission maintenance in patients with …