Angiopoietins, growth factors, and vascular morphology in early arthritis.
U Fearon, K Griosios, A Fraser, R Reece… - The Journal of …, 2003 - jrheum.org
OBJECTIVE: To examine angiogenic growth factors in patients with early, untreated inflammatory
arthritides and controls. METHODS: Synovial membrane (SM) infiltrate and Ang1, Ang2…
arthritides and controls. METHODS: Synovial membrane (SM) infiltrate and Ang1, Ang2…
Angiogenesis markers (VEGF, soluble receptor of VEGF and angiopoietin-1) in very early arthritis and their association with inflammation and joint destruction
OBJECTIVE:: To investigate the involvement of angiogenesis markers in very early arthritis
patients and their relevance to predict further joint destruction. METHODS:: Levels of …
patients and their relevance to predict further joint destruction. METHODS:: Levels of …
[HTML][HTML] Dysregulated miR-125a promotes angiogenesis through enhanced glycolysis
SM Wade, N Ohnesorge, H McLoughlin, M Biniecka… - …, 2019 - thelancet.com
Background Although neoangiogenesis is a hallmark of chronic inflammatory diseases such
as inflammatory arthritis and many cancers, therapeutic agents targeting the vasculature …
as inflammatory arthritis and many cancers, therapeutic agents targeting the vasculature …
Downregulation of the inhibitor of apoptosis protein survivin in keratinocytes and endothelial cells in psoriasis skin following infliximab therapy
T Markham, C Mathews, S Rogers… - British Journal of …, 2006 - academic.oup.com
Background Survivin, an inhibitor of apoptosis protein (IAP), has been implicated in
endothelial cell stability, through inhibition of apoptosis and in cell proliferation. Objectives To …
endothelial cell stability, through inhibition of apoptosis and in cell proliferation. Objectives To …
The pathogenesis of psoriatic arthritis
DJ Veale, U Fearon - The Lancet, 2018 - thelancet.com
Psoriatic arthritis is a chronic, immune-mediated, inflammatory arthropathy that presents
with inflammation of the joints and entheses, including those of the axial skeleton, and is …
with inflammation of the joints and entheses, including those of the axial skeleton, and is …
Ultrasonographic examination of rheumatoid arthritis patients who are free of physical synovitis: power Doppler subclinical synovitis is associated with bone erosion
…, N Iwamoto, K Ichinose, M Tamai, K Arima… - …, 2014 - academic.oup.com
Objective. The aim of this study was to investigate the characteristics of power Doppler (PD)
subclinical synovitis in patients with RA who achieve clinical remission free from physical …
subclinical synovitis in patients with RA who achieve clinical remission free from physical …
Promotion of macrophage activation by Tie2 in the context of the inflamed synovia of rheumatoid arthritis and psoriatic arthritis patients
PA Kabala, B Malvar-Fernandez, AP Lopes… - …, 2020 - academic.oup.com
… Therefore, we determined the consequences of altered Tie2 expression on disease
activity in the K/BxN serum transfer murine arthritis model, using mice in which removal of …
activity in the K/BxN serum transfer murine arthritis model, using mice in which removal of …
Immunopathology of synovitis: from histology to molecular pathways
MG van de Sande, DL Baeten - Rheumatology, 2016 - academic.oup.com
Increased knowledge about pathological processes active in inflammatory joint diseases is
needed to initiate personalized medicine based on targeted treatments in the future. The …
needed to initiate personalized medicine based on targeted treatments in the future. The …
Angiopoietin-2 is highly correlated with inflammation and disease activity in recent-onset rheumatoid arthritis and could be predictive for cardiovascular disease
J Westra, L de Groot, SL Plaxton, E Brouwer… - …, 2011 - academic.oup.com
Objective. To investigate whether serum levels of endothelial cell activation markers in early
RA patients can serve as biomarkers for inflammation and disease activity, and are …
RA patients can serve as biomarkers for inflammation and disease activity, and are …
[CITATION][C] Co-expression of angiopoietins and VEGF determines synovial vascular morphology in inflammatory arthritides.
U Fearon, K Griosios, A Fraser… - ARTHRITIS …, 2000 - LIPPINCOTT WILLIAMS & WILKINS …