Periostin, an extracellular matrix protein belonging to the fasciclin family, has been shown to
play a critical role in the process of remodeling during tissue/organ development or repair. …

Although hydrogen sulfide (H 2 S) is generally thought of in terms of a poisonous gas, it is
endogenously produced in the brain from cysteine by cystathionine β-synthase (CBS). H 2 S …

IL-17–producing CD4 + T helper (Th17) cells have recently been defined as a unique subset
of proinflammatory helper cells whose development depends on signaling initiated by IL-6 …

… Miyagaki T, Sugaya M, Fujita H, Saeki H, Tamaki K. Increased serum thymic stromal
lymphopoietin levels in patients with cutaneous T cell lymphoma. Clin Exp Dermatol 2009;34:539-40…

Interleukin (IL) 25 (IL-17E), a distinct member of the IL-17 cytokine family, plays important
roles in evoking T helper type 2 (Th2) cell–mediated inflammation that features the infiltrations …

Asthma and atopy show epidemiological association and are biologically linked by T-helper
type 2 (T h 2) cytokine-driven inflammatory mechanisms. IL-4 operates through the IL-4 …

BACKGROUND: Subepithelial fibrosis is a cardinal feature of bronchial asthma. Collagen I,
III, and V; fibronectin; and tenascin-C are deposited in the lamina reticularis. Extensive …

The AUXIN RESPONSE FACTOR (ARF) gene family products, together with the AUXIN/INDOLE-3-ACETIC
ACID proteins, regulate auxin-mediated transcriptional activation/repression. …

Background The genetic cause of cerebral autosomal recessive arteriopathy with subcortical
infarcts and leukoencephalopathy (CARASIL), which is characterized by ischemic, …

Type 2 immunity evolved to combat helminth infections by orchestrating a combined
protective response of innate and adaptive immune cells and promotion of parasitic worm …