TNF-α is necessary for induction of coronary artery inflammation and aneurysm formation in an animal model of Kawasaki disease

JS Hui-Yuen, TT Duong, RSM Yeung - The Journal of Immunology, 2006 - journals.aai.org
Kawasaki disease is the most common cause of multisystem vasculitis in childhood. The
resultant coronary artery lesions make Kawasaki disease the leading cause of acquired heart …

Safety and efficacy of belimumab to treat systemic lupus erythematosus in academic clinical practices

JS Hui-Yuen, A Reddy, J Taylor, X Li… - The Journal of …, 2015 - jrheum.org
Objective. To evaluate the use and efficacy of belimumab in academic practices. Belimumab
is a human monoclonal antibody that inhibits soluble B lymphocyte stimulator and has been …

Emerging B-cell therapies in systemic lupus erythematosus

A Bag-Ozbek, JS Hui-Yuen - … and Clinical Risk Management, 2021 - Taylor & Francis
Systemic lupus erythematosus (SLE) is a chronic, multisystem, autoimmune disease of
unknown etiology, whose hallmark is the production of autoantibodies. B cells are promising …

Management of pediatric systemic lupus erythematosus: focus on belimumab

M Guzman, JS Hui-Yuen - Drug Design, Development and Therapy, 2020 - Taylor & Francis
Belimumab (Benlysta ® ) is a fully humanized monoclonal antibody that inhibits B lymphocyte
stimulator (BLyS, also known as B cell-activating factor of the tumor necrosis factor family) …

The safety of COVID‐19 vaccination in immunocompromised children and young adults with immune‐mediated inflammatory disease

B Sahn, Y Lu, JS HuiYuen, J Fishbein… - Acta …, 2023 - Wiley Online Library
Aim To assess safety of COVID‐19 vaccination in paediatric patients with immune‐mediated
inflammatory disease (IMID). Methods Subjects of 5–21 years of age with IMID who …

… league against rheumatism/American college of rheumatology criteria compared to the 1997 American college of rheumatology criteria and the 2012 systemic lupus …

M Ma, JS HuiYuen, JE Cerise, S Iqbal… - Arthritis Care & …, 2020 - Wiley Online Library
Objective Different classification criteria for systemic lupus erythematosus (SLE) have been
proposed for many years. The most widely used and accepted criteria has been the 1997 …

Belimumab in systemic lupus erythematosus: a perspective review

JS Hui-Yuen, XQ Li… - Therapeutic Advances in …, 2015 - journals.sagepub.com
Belimumab (Benlysta ® ) is a fully humanized monoclonal antibody that inhibits B-lymphocyte
stimulator (also known as B cell activating factor of the tumor necrosis factor family) and …

Seroprevalence and clinical outcomes of SARS-CoV-2 in paediatric patients with rheumatic disease

…, BS Gottlieb, K Steigerwald, JS Hui-Yuen - …, 2022 - academic.oup.com
Objectives Immunosuppressed paediatric patients with rheumatic disease (RD) may be at
risk for severe or critical disease related to severe acute respiratory syndrome coronavirus 2 (…

[HTML][HTML] Chromatin landscapes and genetic risk in systemic lupus

JS Hui-Yuen, L Zhu, LP Wong, K Jiang, Y Chen… - Arthritis Research & …, 2016 - Springer
Background Systemic lupus erythematosus (SLE) is a multi-system, complex disease in
which the environment interacts with inherited genes to produce broad phenotypes with inter-…

Use of glucuronidated mycophenolic acid levels for therapeutic monitoring in pediatric lupus nephritis patients

JS Hui-Yuen, T Tran, J Taylor, K Truong… - JCR: Journal of …, 2016 - journals.lww.com
Background/Objectives Mycophenolate mofetil (MMF) is used to treat pediatric-onset lupus
nephritis (pLN). Data are equivocal on the use of plasma mycophenolic acid (MPA) levels as …