Patients with rheumatoid arthritis (RA) have accelerated atherosclerosis. The metabolic
syndrome, a cluster of cardiovascular risk factors, identifies cardiovascular risk. We tested the …

Objective Insulin resistance is increased by inflammation, but the mechanisms are unclear.
The present study was undertaken to test the hypothesis that decreased insulin sensitivity is …

The extent of genetic variation found in drug metabolism genes and its contribution to
interindividual variation in response to medication remains incompletely understood. To better …

We tested the hypothesis that concentrations of adipocytokines are altered in SLE and
associated with coronary atherosclerosis, insulin resistance and inflammation. Concentrations of …

Rationale: Asymptomatic relatives of patients with familial interstitial pneumonia (FIP), the
inherited form of idiopathic interstitial pneumonia, carry increased risk for developing interstitial …

Objective The prevalence of subclinical coronary atherosclerosis is increased in patients
with rheumatoid arthritis (RA), and the increased risk is associated with insulin resistance. …

Osteoprotegerin (OPG), a soluble decoy receptor for receptor activator of nuclear factor κB
ligand, is implicated in the pathogenesis of atherosclerosis. Patients with rheumatoid arthritis (…

Introduction GlycA is a novel inflammatory biomarker measured using nuclear magnetic
resonance (NMR). Its NMR signal primarily represents glycosylated acute phase proteins. GlycA …

Elevated concentrations of inflammatory mediators are characteristic of autoimmune disease
accompanied by chronic or recurrent inflammation. We examined the hypothesis that …

Objective Patients with rheumatoid arthritis (RA) have increased risk of atherosclerotic
cardiovascular disease that is underestimated by the Framingham Risk Score (FRS). We …