What low back pain is and why we need to pay attention

…, S Genevay, D Hoy, J Karppinen, G Pransky, J Sieper… - The Lancet, 2018 - thelancet.com
Low back pain is a very common symptom. It occurs in high-income, middle-income, and low-income
countries and all age groups from children to the elderly population. Globally, years …

Ankylosing spondylitis

J Braun, J Sieper - The Lancet, 2007 - thelancet.com
Ankylosing spondylitis is a common inflammatory rheumatic disease that affects the axial
skeleton, causing characteristic inflammatory back pain, which can lead to structural and …

Prevention and treatment of low back pain: evidence, challenges, and promising directions

…, B Öberg, WC Peul, G Pransky, M Schoene, J Sieper… - The Lancet, 2018 - thelancet.com
Many clinical practice guidelines recommend similar approaches for the assessment and
management of low back pain. Recommendations include use of a biopsychosocial framework …

Efficacy and safety of infliximab in patients with ankylosing spondylitis: results of a randomized, placebo‐controlled trial (ASSERT)

…, B Dijkmans, P Geusens, J Sieper… - … : Official Journal of …, 2005 - Wiley Online Library
Objective The signs and symptoms of ankylosing spondylitis (AS) respond inadequately to
nonsteroidal antiinflammatory drugs, corticosteroids, and disease‐modifying antirheumatic …

Efficacy and safety of adalimumab in patients with ankylosing spondylitis: results of a multicenter, randomized, double‐blind, placebo‐controlled trial

…, A Kivitz, MH Schiff, J Sieper… - … : Official Journal of …, 2006 - Wiley Online Library
Objective To evaluate the safety and efficacy of adalimumab, a fully human recombinant IgG1
monoclonal antibody that specifically targets human tumor necrosis factor, in patients with …

The early disease stage in axial spondylarthritis: results from the German Spondyloarthritis Inception Cohort

…, H Zeidler, J Braun, J Sieper - … : Official Journal of …, 2009 - Wiley Online Library
Objective Ankylosing spondylitis (AS) is diagnosed late, because radiographs of the sacroiliac
joints often do not show definite sacroiliitis at the time of disease onset. The aim of this …

Prevalence of spondylarthropathies in HLA‐B27 positive and negative blood donors

…, M Rudwaleit, A Distler, J Sieper - … : Official Journal of …, 1998 - Wiley Online Library
… Braun J, Sieper J. The sacroiliac joint in the spondyloarthropathies. Curr Opin Rheumatol …
Sieper J, Braun J. Pathogenesis of spondylarthropathies: persistent bacterial antigen, …

Axial spondyloarthritis

J Sieper, D Poddubnyy - The Lancet, 2017 - thelancet.com
The term axial spondyloarthritis covers both patients with non-radiographic and radiographic
axial spondyloarthritis, which is also termed ankylosing spondylitis. The disease usually …

[HTML][HTML] European League Against Rheumatism (EULAR) recommendations for the management of psoriatic arthritis with pharmacological therapies: 2015 update

…, I Olivieri, K Pavelka, G Schett, J Sieper… - Annals of the …, 2016 - ard.bmj.com
Background Since the publication of the European League Against Rheumatism recommendations
for the pharmacological treatment of psoriatic arthritis (PsA) in 2012, new evidence …

Inflammatory back pain in ankylosing spondylitis: a reassessment of the clinical history for application as classification and diagnostic criteria

…, A Metter, J Listing, J Sieper… - … : Official Journal of the …, 2006 - Wiley Online Library
Objective Back pain associated with ankylosing spondylitis (AS) is referred to as inflammatory
back pain (IBP). The value of the clinical history in differentiating IBP from mechanical low …