The Wnt signaling pathway plays an important role not only in embryonic development but
also in the maintenance and differentiation of the stem cells in adulthood. In particular, Wnt …

Moonlighting proteins, characterized by their multiple autonomous functions, have been
detected in bacteria. Surprisingly, many of these proteins are conserved and involved in …

Age-related macular degeneration (AMD) is the leading cause of legal blindness in the elderly
in industrialized countries. AMD is a multifactorial disease influenced by both genetic and …

Background: As reported by the World Health Organization, a novel coronavirus (2019-nCoV)
was identified as the causative virus of Wuhan pneumonia of unknown etiology by …

Effectively releasing the locked polysaccharides from recalcitrant lignocellulose to
fermentable sugars is among the greatest technical and economic barriers to the realization of …

A major challenge in human genetics is to devise a systematic strategy to integrate disease-associated
variants with diverse genomic and biological data sets to provide insight into …

To identify new genetic risk factors for rheumatoid arthritis, we conducted a genome-wide
association study meta-analysis of 5,539 autoantibody-positive individuals with rheumatoid …

Drug delivery has been considered as the key to the clinical success of numerous drugs.[1–3]
In the past decade, with an aim to improve chemotherapy, tremendous effort has been …

To identify rheumatoid arthritis risk loci in European populations, we conducted a meta-analysis
of two published genome-wide association (GWA) studies totaling 3,393 cases and …

Curcumin is a poorly water-soluble drug and its oral bioavailability is very low. A new self-microemulsifying
drug delivery system (SMEDDS) has been successfully developed to …