Concomitant leflunomide therapy in patients with active rheumatoid arthritis despite stable doses of methotrexate: a randomized, double-blind, placebo-controlled trial
…, MH Weisman, WM Bensen, JL Kaine… - Annals of internal …, 2002 - acpjournals.org
Background: Disease-modifying antirheumatic drugs may confer greater benefits when
combined with the antimetabolite methotrexate. Objective: To evaluate the efficacy and safety of …
combined with the antimetabolite methotrexate. Objective: To evaluate the efficacy and safety of …
Immune responses following administration of influenza and pneumococcal vaccines to patients with rheumatoid arthritis receiving adalimumab.
JL Kaine, AJ Kivitz, C Birbara, AY Luo - The Journal of rheumatology, 2007 - jrheum.org
OBJECTIVE: This study compared the immunogenicity of influenza and pneumococcal
vaccines in adult patients with rheumatoid arthritis (RA) receiving adalimumab or placebo. …
vaccines in adult patients with rheumatoid arthritis (RA) receiving adalimumab or placebo. …
Ocrelizumab, a humanized anti‐CD20 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: a phase I/II randomized, blinded, placebo‐controlled …
MC Genovese, JL Kaine, MB Lowenstein… - Arthritis & …, 2008 - Wiley Online Library
Objective Ocrelizumab, a humanized anti‐CD20 monoclonal antibody, was studied in a first‐in‐human
trial in rheumatoid arthritis (RA) patients receiving concomitant methotrexate (MTX…
trial in rheumatoid arthritis (RA) patients receiving concomitant methotrexate (MTX…
Ixekizumab for patients with non-radiographic axial spondyloarthritis (COAST-X): a randomised, placebo-controlled trial
…, KP Flint, M Greenwald, MP Howell, JL Kaine… - The Lancet, 2020 - thelancet.com
Background Ixekizumab, a high-affinity interleukin-17A (IL-17A) monoclonal antibody, has
previously shown efficacy in radiographic axial spondyloarthritis (also known as ankylosing …
previously shown efficacy in radiographic axial spondyloarthritis (also known as ankylosing …
The rapid assessment of disease activity in rheumatology (RADAR) questionnaire
…, D Lewis‐Stevens, JL Kaine - … : Official Journal of …, 1992 - Wiley Online Library
Objective. This study documents the measurement properties of a brief, self‐administered
questionnaire of disease signs and symptoms in patients with rheumatoid arthritis. Methods. …
questionnaire of disease signs and symptoms in patients with rheumatoid arthritis. Methods. …
[HTML][HTML] A phase Ib multiple ascending dose study evaluating safety, pharmacokinetics, and early clinical response of brodalumab, a human anti-IL-17R antibody, in …
…, D Wallace, R Martin, K Phillips, JL Kaine… - Arthritis research & …, 2013 - Springer
Introduction The aim of this study was to evaluate the safety, pharmacokinetics, and clinical
response of brodalumab (AMG 827), a human, anti-IL-17 receptor A (IL-17RA) monoclonal …
response of brodalumab (AMG 827), a human, anti-IL-17 receptor A (IL-17RA) monoclonal …
Evaluation of the safety of rituximab in combination with a tumor necrosis factor inhibitor and methotrexate in patients with active rheumatoid arthritis: results from a …
MW Greenwald, WJ Shergy, JL Kaine… - Arthritis & …, 2011 - Wiley Online Library
Objective To assess the safety of rituximab in combination with a tumor necrosis factor (TNF)
inhibitor and methotrexate (MTX) in patients with rheumatoid arthritis (RA). Methods Adult …
inhibitor and methotrexate (MTX) in patients with rheumatoid arthritis (RA). Methods Adult …
Efficacy and safety of tacrolimus in patients with rheumatoid arthritis: a double‐blind trial
DE Yocum, DE Furst, JL Kaine… - … : Official Journal of …, 2003 - Wiley Online Library
Objective To evaluate the efficacy and safety of tacrolimus as monotherapy in controlling the
signs and symptoms of patients with rheumatoid arthritis (RA). Methods This was a 6‐month…
signs and symptoms of patients with rheumatoid arthritis (RA). Methods This was a 6‐month…
Stratification, specialization, and proliferation of primary keratinocyte cultures. Evidence of a functioning in vitro epidermal cell system.
CL Marcelo, YG Kim, JL Kaine… - The Journal of cell biology, 1978 - rupress.org
A population of neonatal mouse keratinocytes (epidermal basal cells) was obtained by
gentle, short-term trypsin separation of the epidermal and dermal skin compartments and …
gentle, short-term trypsin separation of the epidermal and dermal skin compartments and …
Tacrolimus in rheumatoid arthritis patients receiving concomitant methotrexate: a six‐month, open‐label study
JM Kremer, JS Habros, KS Kolba, JL Kaine… - Arthritis & …, 2003 - Wiley Online Library
Objective To assess the safety of tacrolimus used in combination with oral methotrexate (MTX)
to control the signs and symptoms of rheumatoid arthritis (RA) in patients whose disease …
to control the signs and symptoms of rheumatoid arthritis (RA) in patients whose disease …