Large Genomic Rearrangements in the Hepatocyte Nuclear Factor-1β (TCF2) Gene Are the Most Frequent Cause of Maturity-Onset Diabetes of the Young Type 5
…, E Larger, J Louis, M Nicolino, JF Subra… - Diabetes, 2005 - Am Diabetes Assoc
Maturity-onset diabetes of the young (MODY) 5 is caused by mutations in the TCF2 gene
encoding the transcription factor hepatocyte nuclear factor-1β. However, in 60% of the patients …
encoding the transcription factor hepatocyte nuclear factor-1β. However, in 60% of the patients …
Long‐term outcomes among participants in the WEGENT trial of remission‐maintenance therapy for granulomatosis with polyangiitis (Wegener's) or microscopic …
…, P Roblot, M Ruivard, JF Subra… - Arthritis & …, 2016 - Wiley Online Library
Objective Findings from the WEGENT trial and other short‐term studies have suggested that
azathioprine (AZA) or methotrexate (MTX) could effectively maintain remission of …
azathioprine (AZA) or methotrexate (MTX) could effectively maintain remission of …
Post-transplantation lymphoproliferative disorder after kidney transplantation: report of a nationwide French registry and the development of a new prognostic score
…, I Etienne, MC Moal, L Albano, JF Subra… - Journal of clinical …, 2013 - ascopubs.org
Purpose Post-transplantation lymphoproliferative disorder (PTLD) is associated with
significant mortality in kidney transplant recipients. We conducted a prospective survey of the …
significant mortality in kidney transplant recipients. We conducted a prospective survey of the …
[HTML][HTML] Antithrombotic effects of hydroxychloroquine in primary antiphospholipid syndrome patients
…, J Voswinkel, D Henrion, JF Subra… - Journal of Thrombosis …, 2013 - jthjournal.org
Several studies have shown an important risk of thrombosis relapse in antiphospholipid
syndrome (APS)[1, 2], and the need for secondary prophylaxis [3]. Hydroxychloroquine (HCQ) is …
syndrome (APS)[1, 2], and the need for secondary prophylaxis [3]. Hydroxychloroquine (HCQ) is …
[HTML][HTML] Clusterin facilitates apoptotic cell clearance and prevents apoptotic cell-induced autoimmune responses
…, E Garo, I Fremaux, A Chevailler, JF Subra… - Cell death & …, 2016 - nature.com
Clusterin (Clu), an extracellular chaperone, exhibits characteristics of soluble innate immunity
receptors, as assessed by its ability to bind some bacteria strains. In this study, we report …
receptors, as assessed by its ability to bind some bacteria strains. In this study, we report …
Splenectomy and/or cyclophosphamide as salvage therapies in thrombotic thrombocytopenic purpura: the French TMA Reference Center experience
…, L Galicier, B Guidet, JL Baudel, JF Subra… - …, 2012 - Wiley Online Library
BACKGROUND: The objective was to assess the efficacy and safety of splenectomy and
cyclophosphamide as salvage therapies in severe thrombotic thrombocytopenic purpura (TTP). …
cyclophosphamide as salvage therapies in severe thrombotic thrombocytopenic purpura (TTP). …
[HTML][HTML] Low serum complement C3 levels at diagnosis of renal ANCA-associated vasculitis is associated with poor prognosis
…, A Chevailler, A Croue, F Tollis, J Sayegh, JF Subra - PLoS …, 2016 - journals.plos.org
Background Recent studies have demonstrated the key role of the complement alternative
pathway (cAP) in the pathophysiology of experimental ANCA-associated vasculitis (AAV). …
pathway (cAP) in the pathophysiology of experimental ANCA-associated vasculitis (AAV). …
Complement alternative pathway in ANCA-associated vasculitis: Two decades from bench to bedside
…, AS Garnier, A Chevailler, P Jeannin, JF Subra… - Autoimmunity …, 2020 - Elsevier
Anti-neutrophil cytoplasmic autoantibodies (ANCA)-associated vasculitides (AAVs) are small
vessel vasculitides involving predominantly ear-nose-throat, kidneys, lungs and nerves. …
vessel vasculitides involving predominantly ear-nose-throat, kidneys, lungs and nerves. …
IL-26 confers proinflammatory properties to extracellular DNA
…, P Pignon, A Savina, S Blanchard, JF Subra… - The Journal of …, 2017 - journals.aai.org
In physiological conditions, self-DNA released by dying cells is not detected by intracellular
DNA sensors. In chronic inflammatory disorders, unabated inflammation has been …
DNA sensors. In chronic inflammatory disorders, unabated inflammation has been …
Systemic and immune manifestations in myelodysplasia: a multicenter retrospective study
…, H Lévesque, M Hamidou, JF Subra… - Arthritis care & …, 2011 - Wiley Online Library
Objective The presence of systemic and/or immune manifestations in myelodysplasia has
been currently reported. The influence of these manifestations on the natural outcome of …
been currently reported. The influence of these manifestations on the natural outcome of …