Prototype Demonstration of Transgenic Resistance to the Nematode Radopholus similis Conferred on Banana by a Cystatin

HJ Atkinson, S Grimwood, K Johnston, J Green - Transgenic research, 2004 - Springer
Cavendish banana was transformed using Agrobacterium tumefaciens to express a protein
engineered rice cystatin (OcIΔD86) of value for control of plant parasitic nematodes. …

[HTML][HTML] Super-enhancers and broad H3K4me3 domains form complex gene regulatory circuits involving chromatin interactions

…, N Bertin, A Ramadass, E Hunter, J Green… - Scientific reports, 2017 - nature.com
Stretched histone regions, such as super-enhancers and broad H3K4me3 domains, are
associated with maintenance of cell identity and cancer. We connected super-enhancers and …

Guidelines for blood test monitoring of methotrexate toxicity in juvenile idiopathic arthritis.

O Ortiz-Alvarez, K Morishita, G Avery, J Green… - The Journal of …, 2004 - jrheum.org
OBJECTIVE: To assess the utility of the American College of Rheumatology guidelines for
monitoring methotrexate (MTX)-related toxicity in a cohort of children with juvenile idiopathic …

[HTML][HTML] Development and validation of blood-based predictive biomarkers for response to PD-1/PD-L1 checkpoint inhibitors: evidence of a universal systemic core of …

…, ME Chatziioannou, A Gebregzabhar, M Issa, J Green… - Cancers, 2023 - mdpi.com
Simple Summary Immune checkpoint inhibitors (ICIs) offer high efficacy of cancer treatment,
but their use is limited to a subset of patients who respond well to the resetting of the …

[HTML][HTML] A recurring rollercoaster ride: a qualitative study of the emotional experiences of parents of children with juvenile idiopathic arthritis

…, M Gibbon, R Berard, R Jurencak, J Green… - Pediatric …, 2016 - Springer
Background Despite the wealth of clinical research carried out in children with juvenile
idiopathic arthritis (JIA), little is known about the emotional experiences of their parents. This …

Environmental biosafety and transgenic potato in a centre of diversity for this crop

C Celis, M Scurrah, S Cowgill, S Chumbiauca, J Green… - Nature, 2004 - nature.com
The Nuffield Council on Bioethics 1 , 2 suggests that introgression of genetic material into
related species in centres of crop biodiversity is an insufficient justification to bar the use of …

[HTML][HTML] Chromosome conformation signatures define predictive markers of inadequate response to methotrexate in early rheumatoid arthritis

C Carini, E Hunter, AS Ramadass, J Green… - Journal of translational …, 2018 - Springer
Background There is a pressing need in rheumatoid arthritis (RA) to identify patients who
will not respond to first-line disease-modifying anti-rheumatic drugs (DMARD). We explored …

Expression of a plant cystatin confers partial resistance to Globodera, full resistance is achieved by pyramiding a cystatin with natural resistance

PE Urwin, J Green, HJ Atkinson - Molecular Breeding, 2003 - Springer
Constructs based on a cysteine proteinase inhibitor (cystatin) from sunflower and a protein
engineered variant of a rice cystatin (Oc-IΔD86) conferred similar levels of resistance on …

[HTML][HTML] Comparative molecular cell-of-origin classification of diffuse large B-cell lymphoma based on liquid and tissue biopsies

E Hunter, R McCord, AS Ramadass, J Green… - Translational Medicine …, 2020 - Springer
Background Diffuse large B-cell lymphoma (DLBCL) is a heterogenous blood cancer, but
can be broadly classified into two main subtypes, germinal center B-cell-like (GCB) and …

[HTML][HTML] Transgenic potatoes for potato cyst nematode control can replace pesticide use without impact on soil quality

J Green, D Wang, CJ Lilley, PE Urwin, HJ Atkinson - PLoS One, 2012 - journals.plos.org
Current and future global crop yields depend upon soil quality to which soil organisms make
an important contribution. The European Union seeks to protect European soils and their …