Background New onset or worsening of psoriasis has been reported in patients treated with
tumor necrosis factor α (TNF-α) inhibitors for a variety of rheumatologic conditions. There is …

In neonatal rodents, the beta-cell mass undergoes a phase of remodeling that includes a
wave of apoptosis. Using both mathematical modeling and histochemical detection methods, …

Although chloroquine, hydroxychloroquine and quinacrine were originally developed for the
treatment of malaria, these medications have been used to treat skin disease for over 50 …

Autoimmune (type 1) diabetes mellitus results from the destruction of insulin-producing
pancreatic β cells by T lymphocytes. Prediction of cell-mediated autoimmune diseases by direct …

… We identified 71 patients admitted with a possible diagnosis of SJS/TEN between January
2001 … Dr Dutz is a senior scientist at the Child and Family Research Institute. We thank Boris …

Objectives. To compare obesity among individuals with PsA, psoriasis (PsO), RA and the
general population (n), and identify correlates of obesity among individuals with PsO and PsA. …

Accumulating evidence supports that the intestinal microbiome is involved in Type 1 diabetes
(T1D) pathogenesis through the gut-pancreas nexus. Our aim was to determine whether …

25-Dihydroxyvitamin D 3 is immunosuppressive both in vivo and in vitro. Topical vitamin D
analogs such as calcipotriol alter keratinocyte function, but their effects on cutaneous immune …

Macrophages limit inflammatory responses by clearing apoptotic cells. Deficiencies in
apoptotic cell phagocytosis have been linked to autoimmunity. In this study, we determined the …

Abnormal placentation results in either inadequate (consequences: recurrent miscarriage,
intrauterine growth restriction, and preeclampsia) or overzealous (consequences: placenta …