Background There has been much interest in screening populations for disease-associated
mutations. A favoured candidate has been the HFE gene, mutations of which are the most …

Microvascular integrity is lost during focal cerebral ischemia. The degradation of the basal
lamina and extracellular matrix are, in part, responsible for the loss of vascular integrity. Matrix …

OBJECTIVES: Most individuals with interstitial cystitis (IC) have both pelvic pain and urinary
urgency/frequency, and many have dyspareunia. Existing questionnaires designed to …

Cancer sera contain antibodies which react with a unique group of autologous cellular antigens
called tumor-associated antigens (TAAs). This study determines whether a mini-array of …

A survey directed at determining the natural history of interstitial cystitis was conducted at our
clinic. Information on demographics, risk factors, symptoms, pain and psychosocial factors …

Hairy cell leukemia is a chronic B-cell disorder that follows an indolent, but progressive
course. Cladribine (2-chlorodeoxyadenosine) induces complete remissions in the majority of …

The asymptotic distributions of camér-von Mises type statistics based on the productlimit
estimate of the distribution function of a certain class of randomly censored observations are …

Background and Purpose— Focal cerebral ischemia causes microvessel matrix degradation
and generates proteases known to degrade this matrix. However, proof that the proteases …

Local environmental conditions contribute to the activation state of cells. Extracellular matrix
glycoproteins participate in cell-cell boundaries within the microvascular and extravascular …

Platelet activation altered the binding of three monoclonal antibodies (monovalent Fab'
fragment) directed against the glycoprotein (GP) IIb/IIIa complex. An increased binding of two- to …