Olive oil (OO) is the most representative food in the traditional Mediterranean Diet (MedDiet).
Increasing evidences suggest that monounsaturated fatty acids (MUFA) as a nutrient, OO …

Links between short sleep duration and obesity, type 2 diabetes, hypertension, and cardiovascular
disease may be mediated through changes in dietary intake. This review provides an …

The specific metabolic contribution of consuming different energy-yielding macronutrients (namely,
carbohydrates, protein and lipids) to obesity is a matter of active debate. In this …

Background High plasma HDL cholesterol is associated with reduced risk of myocardial
infarction, but whether this association is causal is unclear. Exploiting the fact that genotypes are …

In vitro data suggest protective roles for vitamins K and D in inflammation. To examine
associations between vitamins K and D and inflammation in vivo, the authors used multiple linear …

Mixed linear model (MLM) methods have proven useful in controlling for population structure
and relatedness within genome-wide association studies. However, MLM-based methods …

Blood concentrations of lipoproteins and lipids are heritable 1 risk factors for cardiovascular
disease 2 , 3 . Using genome-wide association data from three studies (n = 8,816 that …

Background: The regulatory function of the endothelium is altered in hypercholesterolemia,
and the subsequent endothelial dysfunction plays a central role in the development of …

Blood low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol
and triglyceride levels are risk factors for cardiovascular disease. To dissect the polygenic …

Metabolic responses to food influence risk of cardiometabolic disease, but large-scale high-resolution
studies are lacking. We recruited n = 1,002 twins and unrelated healthy adults in …