Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome-wide
association study of 41,917 bipolar disorder cases and 371,549 controls of European …

Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide
association study (GWAS) including 20,352 cases and 31,358 controls of European descent, …

Lung cancer is the most common cause of cancer death worldwide, with over one million
cases annually 1 . To identify genetic factors that modify disease risk, we conducted a genome-…

Objective To examine the efficacy and safety of the humanized anti–interleukin‐6 receptor
antibody tocilizumab combined with conventional disease‐modifying antirheumatic drugs (…

Objective To assess the safety, tolerability, biologic activity, and efficacy of belimumab in
combination with standard of care therapy (SOC) in patients with active systemic lupus …

We carried out a genome-wide association study of lung cancer (3,259 cases and 4,159
controls), followed by replication in 2,899 cases and 5,573 controls. Two uncorrelated disease …

Three genetic loci for lung cancer risk have been identified by genome-wide association
studies (GWAS), but inherited susceptibility to specific histologic types of lung cancer is not well …

Although several lung cancer susceptibility loci have been identified, much of the heritability
for lung cancer remains unexplained. Here 14,803 cases and 12,262 controls of European …

We conducted imputation to the 1000 Genomes Project of four genome-wide association
studies of lung cancer in populations of European ancestry (11,348 cases and 15,861 controls) …

Bipolar disorder (BD) is a common and highly heritable mental illness and genome-wide
association studies (GWAS) have robustly identified the first common genetic variants involved …