[HTML][HTML] The complement regulator factor H binds to the surface protein OspE of Borrelia burgdorferi

…, T Meri, T Heikkilä, A Alitalo, J Panelius… - Journal of Biological …, 2001 - ASBMB
Spirochete bacteria of the Borrelia burgdorferi sensu lato complex cause Lyme borreliosis.
The three pathogenic subspecies Borrelia garinii, Borrelia afzelii, and Borrelia burgdorferi …

Complement evasion strategies of Borrelia burgdorferi sensu lato

V Dulipati, S Meri, J Panelius - FEBS letters, 2020 - Wiley Online Library
Borreliosis (Lyme disease) is a spirochetal disease caused by the species complex of
Borrelia burgdorferi transmitted by Ixodes spp. ticks. Recorded to be the most common tick‐borne …

Replication of GWAS-identified systemic lupus erythematosus susceptibility genes affirms B-cell receptor pathway signalling and strengthens the role of IRF5 in …

…, M Zucchelli, S Koskenmies, J Panelius… - …, 2012 - academic.oup.com
Objective. A large number of genes, including several not previously implicated in SLE
susceptibility, have recently been identified or confirmed by genome-wide association studies (…

[HTML][HTML] Complement system in dermatological diseases–fire under the skin

J Panelius, S Meri - Frontiers in medicine, 2015 - frontiersin.org
The complement system plays a key role in several dermatological diseases. Overactivation,
deficiency, or abnormality of the control proteins are often related to a skin disease. …

Tyrosine kinase 2 and interferon regulatory factor 5 polymorphisms are associated with discoid and subacute cutaneous lupus erythematosus

…, L Jeskanen, L Berglind, J Panelius… - Experimental …, 2010 - Wiley Online Library
Please cite this paper as: Tyrosine kinase 2 and interferon regulatory factor 5 polymorphisms
are associated with discoid and subacute cutaneous lupus erythematosus. Experimental …

Genome‐wide association study identifies new susceptibility loci for cutaneous lupus erythematosus

…, W Lieb, A Franke, A Ranki, J Panelius… - Experimental …, 2015 - Wiley Online Library
Cutaneous lupus erythematosus ( CLE ) is a chronic autoimmune disease of the skin with
typical clinical manifestations. Here, we genotyped 906 600 single nucleotide polymorphisms ( …

Evidence for genetic association and interaction between the TYK2 and IRF5 genes in systemic lupus erythematosus

…, C Orsmark-Pietras, L Berglind, J Panelius… - The Journal of …, 2009 - jrheum.org
Objective. Several candidate genes have been implicated in susceptibility for systemic
lupus erythematosus (SLE), a complex autoimmune disease. The proposed genes include …

Species-SpecificSerodiagnosis of Lyme Arthritis and Neuroborreliosis Due to Borreliaburgdorferi Sensu Stricto, B. afzelii, and B.garinii by Using Decorin Binding …

…, I Seppälä, H Saxen, J Panelius… - Journal of clinical …, 2002 - Am Soc Microbiol
The antigenic potential of decorin binding protein A (DbpA) was evaluated in serodiagnosis
of human Lyme borreliosis (LB). The dbpA was cloned and sequenced from the three …

[HTML][HTML] Polymorphisms of the ITGAM Gene Confer Higher Risk of Discoid Cutaneous Than of Systemic Lupus Erythematosus

…, A Hellquist, S Koskenmies, E Einarsdottir, J Panelius… - PLoS …, 2010 - journals.plos.org
Background Lupus erythematosus (LE) is a heterogeneous disease ranging from mainly
skin-restricted manifestations (discoid LE [DLE] and subacute cutaneous LE) to a progressive …

Clinical and laboratory characteristics of Finnish lupus erythematosus patients with cutaneous manifestations

S Koskenmies, TM Järvinen, P Onkamo, J Panelius… - Lupus, 2008 - journals.sagepub.com
Our objective was to characterize clinical features, laboratory findings, concomitant
autoimmune diseases, and smoking habits of lupus erythematosus subgroups in genetically …