User profiles for J. WORTHINGTON

JJ Worthington

Lancaster University
Verified email at lancaster.ac.uk
Cited by 2637

TGFβ: a sleeping giant awoken by integrins

JJ Worthington, JE Klementowicz, MA Travis - Trends in biochemical …, 2011 - cell.com
Transforming growth factor beta (TGFβ) controls numerous cellular responses, including
proliferation, differentiation, apoptosis and migration. This cytokine is produced by many …

Nesfatin-1, a unique regulatory neuropeptide of the brain

A Pałasz, M Krzystanek, J Worthington, B Czajkowska… - Neuropeptides, 2012 - Elsevier
Nesfatin-1, a newly discovered NUCB2-derived satiety neuropeptide is expressed in
several neurons of forebrain, hindbrain, brainstem and spinal cord. This novel anorexigenic …

[HTML][HTML] Regulation of TGFβ in the immune system: an emerging role for integrins and dendritic cells

JJ Worthington, TM Fenton, BI Czajkowska… - Immunobiology, 2012 - Elsevier
Regulation of an immune response requires complex crosstalk between cells of the innate
and adaptive immune systems, via both cell–cell contact and secretion of cytokines. An …

Randomized controlled trial of mindfulness meditation for generalized anxiety disorder: effects on anxiety and stress reactivity

…, LK Morris, DJ Robinaugh, JJ Worthington… - The Journal of clinical …, 2013 - psychiatrist.com
Objective: Mindfulness meditation has met increasing interest as a therapeutic strategy for
anxiety disorders, but prior studies have been limited by methodological concerns, including a …

Residual symptoms in depressed patients who respond acutely to fluoxetine

…, JE Alpert, JA Pava, JJ Worthington… - Journal of Clinical …, 1999 - psychiatrist.com
Background: Antidepressants have unequivocal efficacy as compared with placebo, but
many patients have residual symptoms despite a robust response to antidepressant therapy. …

The epidemiology of rheumatoid arthritis in Rochester Minnesota: a study of incidence, prevalence, and mortality

A Linos, JW Worthington, M O'FALLON… - American journal of …, 1980 - academic.oup.com
A study of the incidence and prevalence of rheumatoid arthritis conducted in Rochester, MN,
during the period 1950 through 1974 revealed an average annual incidence rate of 28.1 …

[BOOK][B] Managing the brief for better design

A Blyth, J Worthington - 2002 - taylorfrancis.com
Based on extensive research, this book offers an understanding of the briefing process and
its importance to the built environment. The coverage extends beyond new build covering …

National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Australian clinical guidelines for the diagnosis and management of atrial …

…, JM Kalman, P Sanders, J Worthington… - Medical Journal of …, 2018 - Wiley Online Library
Introduction: Atrial fibrillation (AF) is increasing in prevalence and is associated with
significant morbidity and mortality. The optimal diagnostic and treatment strategies for AF are …

Timing of onset of antidepressant response with fluoxetine treatment

…, JE Alpert, J Gordon, JJ Worthington… - American Journal of …, 2000 - Am Psychiatric Assoc
OBJECTIVE: The purpose of this study was to assess the time until onset of antidepressant
response with fluoxetine treatment. METHOD: The authors evaluated 182 outpatients with …

Azathioprine with prednisone for polymyositis: a controlled, clinical trial

TW BUNCH, JW WORTHINGTON… - Annals of internal …, 1980 - acpjournals.org
Excerpt A controlled, prospective, double-blind, therapeutic trial of azathioprine was conducted
in the initial therapy of polymyositis. Sixteen patients received 60 mg prednisone per day …