User profiles for J. Pelletier

James F Pelletier

Postdoc, Centro Nacional de Biotecnología
Verified email at cnb.csic.es
Cited by 3015

Role of proinflammatory cytokines in the pathophysiology of osteoarthritis

…, J Martel-Pelletier, D Lajeunesse, JP Pelletier… - Nature Reviews …, 2011 - nature.com
Osteoarthritis (OA) is associated with cartilage destruction, subchondral bone remodeling
and inflammation of the synovial membrane, although the etiology and pathogenesis …

Low-temperature sterilization using gas plasmas: a review of the experiments and an analysis of the inactivation mechanisms

M Moisan, J Barbeau, S Moreau, J Pelletier… - International journal of …, 2001 - Elsevier
Utilizing an ionized gas (plasma) to achieve sterilization is an alternative to conventional
sterilization means as far as sterilization of heat-sensitive materials and innocuity of sterilizing …

The role of cytokines in osteoarthritis pathophysiology

JC Fernandes, J Martel‐Pelletier, JP Pelletier - Biorheology, 2002 - content.iospress.com
Morphological changes observed in OA include cartilage erosion as well as a variable degree
of synovial inflammation. Current research attributes these changes to a complex network …

[HTML][HTML] Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis

…, BO Khatri, X Montalban, J Pelletier… - … England Journal of …, 2010 - Mass Medical Soc
Background Fingolimod (FTY720), a sphingosine-1-phosphate–receptor modulator that
prevents lymphocyte egress from lymph nodes, showed clinical efficacy and improvement on …

WT-1 is required for early kidney development

…, H Sariola, JM Loring, M Maeda, J Pelletier… - Cell, 1993 - cell.com
in humans, germiine mutations of the WT-7 tumor suppressor gene are associated with both
Wiims’ tumors and urogenital malformations. To develop a model system for the molecular …

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

KM Call, T Glaser, CY Ito, AJ Buckler, J Pelletier… - Cell, 1990 - cell.com
We have isolated a series of genomic and cDNA clones mapping within the boundaries of
constitutional and tumor deletions that define the Wilms' tumor locus on human chromsome 11 …

[HTML][HTML] Osteoarthritis cartilage histopathology: grading and staging

…, S Gay, SA Jimenez, K Ostergaard, JP Pelletier… - Osteoarthritis and …, 2006 - Elsevier
OBJECTIVE: Current osteoarthritis (OA) histopathology assessment methods have difficulties
in their utility for early disease, as well as their reproducibility and validity. Our objective …

Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA

J Pelletier, N Sonenberg - Nature, 1988 - nature.com
… Translations were performed and processed as described by Pelletier et al“ with mRNA
concentrations of 30 g ml". c, Translation of Xba I (5'CTCTAGAG3") linker derivatives of P2CAT in …

IL-17 stimulates the production and expression of proinflammatory cytokines, IL-β and TNF-α, by human macrophages

…, JA Di Battista, J Martel-Pelletier… - The Journal of …, 1998 - journals.aai.org
IL-17 is a newly described, T cell-derived cytokine with ill-defined physiologic properties. As
such, we examined the release of proinflammatory mediators by human macrophages in …

[PDF][PDF] Osteoarthritis, an inflammatory disease: potential implication for the selection of new therapeutic targets

JP Pelletier, J Martel‐Pelletier… - Arthritis & Rheumatism …, 2001 - stem-art.com
… Haraoui B, Pelletier JP, Cloutier JM, Faure MP, MartelPelletier J. Synovial membrane
histology and immunopathology in rheumatoid arthritis and osteoarthritis: in vivo effects of …