Description of 214 cases of autoimmune congenital heart block: results of the French neonatal lupus syndrome

…, J Ninet, N Pangaud, T Papo, JL Pellegrin… - Autoimmunity …, 2015 - Elsevier
Background Cardiac neonatal lupus syndrome is due to anti-SSA or SSB antibodies and
mainly includes congenital heart block (CHB) and dilated cardiomyopathy (DCM). Its optimal …

Molecular mechanisms controlling the cell cycle: fundamental aspects and implications for oncology

…, F Belloc, JL Pellegrin, J Reiffers - … : journal de la Societe …, 2001 - europepmc.org
Comprehension of cell cycle regulation mechanisms has progressed very quickly these past
few years and regulators of the cell cycle have gained widespread importance in cancer. …

HIV-infected adults with a CD4 cell count greater than 500 cells/mm3 on long-term combination antiretroviral therapy reach same mortality rates as the general …

…, M Dupon, P Dellamonica, JL Pellegrin… - JAIDS Journal of …, 2007 - journals.lww.com
Objective: To compare mortality rates in combination antiretroviral therapy (cART)-treated
HIV-infected adults with mortality in the general population according to the level of CD4 cell …

Th1 (IL-2, interferon-gamma (IFN-γ)) and Th2 (IL-10, IL-4) cytokine production by peripheral blood mononuclear cells (PBMC) from patients with systemic lupus …

JF Viallard, JL Pellegrin, V Ranchin… - Clinical & …, 1999 - academic.oup.com
We investigated the production of IL-2, IFN-γ, IL-10 and IL-4 by PBMC from 24 patients with
SLE and 10 healthy individuals. Basal and mitogen-stimulated (lipopolysaccharide and …

Increase in activated CD8+ T lymphocytes expressing perforin and granzyme B correlates with disease activity in patients with systemic lupus erythematosus

…, JF Viallard, JL Taupin, JL Pellegrin… - … : Official Journal of …, 2005 - Wiley Online Library
Objective Cytotoxic T lymphocyte–mediated killing using granzyme B has recently been
proposed to be a preferential and selective source of autoantigens in systemic autoimmune …

[PDF][PDF] OX40 ligand contributes to human lupus pathogenesis by promoting T follicular helper response

…, P Merville, T Schaeverbeke, JF Viallard, JL Pellegrin… - Immunity, 2015 - cell.com
… FV, J.-LP, and J.-FM provided adult SLE samples and clinical information. VP provided
pediatric SLE blood samples and clinical information. … J. Liu for discussions. We thank S. …

Platelet CD154 potentiates interferon-α secretion by plasmacytoid dendritic cells in systemic lupus erythematosus

…, JF Viallard, C Goulvestre, JL Pellegrin… - Science translational …, 2010 - science.org
Systemic lupus erythematosus (SLE) is a systemic inflammatory autoimmune disease
characterized by the involvement of multiple organs and an immune response against nuclear …

Plasma lipids in HIV‐infected patients: a prospective study in 95 patients

J Constans, JL Pellegrin, E Peuchant… - European journal of …, 1994 - Wiley Online Library
The present study aimed to determine plasma lipid levels in 95 HIV‐infected patients divided
into four groups according to the CD4 lymphocyte counts comparatively to a control group …

Predominance of CD8+ T lymphocytes among periglomerular infiltrating cells and link to the prognosis of class III and class IV lupus nephritis

…, JF Moreau, C Combe, JL Pellegrin… - … : Official Journal of …, 2007 - Wiley Online Library
Objective Recent studies have revealed a potential implication of CD8+ T lymphocytes in the
pathogenesis of systemic lupus erythematosus (SLE) through their ability to induce tissue …

Increased soluble and platelet-associated CD40 ligand in essential thrombocythemia and reactive thrombocytosis

…, JL Pellegrin, AT Nurden, J Ripoche - Blood, The Journal …, 2002 - ashpublications.org
CD40 ligand (CD40L) is expressed on activated CD4 + T lymphocytes and at the activated
platelet surface. A circulating soluble form of CD40L (sCD40L) is generated by the way of a …