[HTML][HTML] Role of leptin in female reproduction

…, F Sánchez-Jiménez, J Maymó… - Clinical Chemistry and …, 2015 - degruyter.com
Reproductive function is dependent on energy resources. The role of weight, body composition,
fat distribution and the effect of diet have been largely investigated in experimental …

Sacroiliitis associated with axial spondyloarthropathy: new concepts and latest trends

M Navallas, J Ares, B Beltrán, MP Lisbona, J Maymó… - Radiographics, 2013 - pubs.rsna.org
The sacroiliac joints are involved in most cases of axial spondyloarthropathy, the first
manifestation usually being sacroiliitis. A finding of sacroiliitis at radiography is the classic …

leptin gene expression in the placenta–regulation of a key hormone in trophoblast proliferation and survival

JL Maymo, AP Pérez, Y Gambino, JC Calvo… - Placenta, 2011 - Elsevier
Leptin is a 16000 MW protein originally described as an adipocyte-derived signaling molecule
for the central control of metabolism. However, pleiotropic effects of leptin have been …

Antiangiogenic effects of anti–tumor necrosis factor α therapy with infliximab in psoriatic arthritis

…, J Maymó, J Gratacós, J Mezquita… - Arthritis & …, 2004 - Wiley Online Library
Objective Neovascularization, with an increased number of synovial vessels with a
characteristic morphology, seems to contribute to the progression of psoriatic arthritis (PsA). …

Leptin prevents apoptosis of trophoblastic cells by activation of MAPK pathway

A Pérez-Pérez, J Maymó, JL Dueñas… - Archives of Biochemistry …, 2008 - Elsevier
Leptin (Ob), the peripheral signal produced by the adipocyte to regulate energy metabolism,
can also be produced by placenta, where it may work as an autocrine hormone. Recently, …

17Beta-estradiol enhances leptin expression in human placental cells through genomic and nongenomic actions

YP Gambino, JL Maymó, A Pérez-Pérez… - Biology of …, 2010 - academic.oup.com
The process of embryo implantation and trophoblast invasion is considered the most limiting
factor in the establishment of pregnancy. Leptin was originally described as an adipocyte-…

Leptin stimulates protein synthesis-activating translation machinery in human trophoblastic cells

A Pérez-Pérez, J Maymó, Y Gambino… - Biology of …, 2009 - academic.oup.com
Leptin was originally considered as an adipocyte-derived signaling molecule for the central
control of metabolism. However, pleiotropic effects of leptin have been identified in …

[HTML][HTML] Involvement of leptin in the molecular physiology of the placenta

M Schanton, JL Maymó, A Pérez-Pérez… - …, 2018 - rep.bioscientifica.com
Leptin is a homeostatic regulator in the placenta where it promotes proliferation, protein
synthesis and the expression of tolerogenic maternal response molecules such as HLA-G. …

Insulin and leptin signaling in placenta from gestational diabetic subjects

A Pérez-Pérez, P Guadix, J Maymó… - Hormone and …, 2016 - thieme-connect.com
Insulin and leptin receptors are known to share signaling pathways, such as JAK2/STAT-3 (Janus
kinase2/signal transduction and activator of transcription3), MAPK (Mitogen activated …

Activated translation signaling in placenta from pregnant women with gestational diabetes mellitus: possible role of leptin

A Pérez-Pérez, JL Maymo, YP Gambino… - Hormone and …, 2013 - thieme-connect.com
Placentas from gestational diabetes (GDM) suffer from structural and functional changes
including overgrowth. That is why we aimed to study [ 3 H]-leucine incorporation into protein in …