User profiles for J. HILL GASTON
 | Hill Gastonprofessor rheumatology university of cambridge Verified email at medschl.cam.ac.uk Cited by 4139 |
Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis
…, JC Goodall, JS Hill Gaston - Arthritis & Rheumatism …, 2009 - Wiley Online Library
… JS Hill Gaston … JS Hill Gaston … Gaston had full access to all of the data in the study
and takes responsibility for the integrity of the data and the accuracy of the data analysis. …
and takes responsibility for the integrity of the data and the accuracy of the data analysis. …
[HTML][HTML] β-Glucan size controls dectin-1-mediated immune responses in human dendritic cells by regulating IL-1β production
…, R Chee, DL Williams, JS Hill Gaston… - Frontiers in …, 2017 - frontiersin.org
Dectin-1/CLEC7A is a pattern recognition receptor that recognizes β-1,3 glucans, and its
stimulation initiates signaling events characterized by the production of inflammatory cytokines …
stimulation initiates signaling events characterized by the production of inflammatory cytokines …
CD27 expression discriminates between regulatory and non‐regulatory cells after expansion of human peripheral blood CD4+ CD25+ cells
…, TNF Shaw, LB Jarvis, G Kaur, JS Hill Gaston - …, 2007 - Wiley Online Library
It is clear that regulatory T cells (Treg) have an important role in preventing autoimmunity
and modulating responses to pathogens. Full characterization of Treg cell function in human …
and modulating responses to pathogens. Full characterization of Treg cell function in human …
The role of T-Iymphocytes in rheumatoid arthritis
M Salmon, JS Hill Gaston - British medical bulletin, 1995 - academic.oup.com
The role of T lymphocytes in the pathology of rheumatoid arthritis (RA) is controversial. To
some extent this has resulted from contradictory data, but even where specific points of fact are …
some extent this has resulted from contradictory data, but even where specific points of fact are …
Consistent patterns of expression of HLA class I free heavy chains in healthy individuals and raised expression in spondyloarthropathy patients point to physiological …
…, JS Hill Gaston, A Moffett, J Trowsdale… - …, 2006 - academic.oup.com
Objectives. Major histocompatibility complex class I (MHC-I) proteins exist at the cell surface
in antigen presenting forms and as β 2 m-independent free heavy chains (FHCs). FHCs …
in antigen presenting forms and as β 2 m-independent free heavy chains (FHCs). FHCs …
Clinical and experimental evidence for persistent Yersinia infection in reactive arthritis
JS Hill Gaston, C Cox, K Granfors - Arthritis & Rheumatism …, 1999 - Wiley Online Library
The findings of bacterial antigens in the joint and persistent triggering infection elsewhere in
the body are thought to be important in the pathogenesis of reactive arthritis (ReA). We …
the body are thought to be important in the pathogenesis of reactive arthritis (ReA). We …
Breaking the rules: the unconventional recognition of HLA‐B27 by CD4+ T lymphocytes as an insight into the pathogenesis of the spondyloarthropathies
LH Boyle, JS Hill Gaston - Rheumatology, 2003 - academic.oup.com
Despite extensive research, it remains unclear why a small proportion of HLA‐ B27 +
individuals develop spondyloarthropathies (SpA). Because the function of HLA‐B27, as a major …
individuals develop spondyloarthropathies (SpA). Because the function of HLA‐B27, as a major …
Characterization of plasmacytoid dendritic cells in inflammatory arthritis synovial fluid
CH Van Krinks, MK Matyszak, JS Hill Gaston - Rheumatology, 2004 - academic.oup.com
… JS Hill Gaston JS Hill Gaston … CH Van Krinks, MK Matyszak, JS Hill Gaston, Characterization
of plasmacytoid dendritic cells in inflammatory arthritis synovial fluid, Rheumatology, …
of plasmacytoid dendritic cells in inflammatory arthritis synovial fluid, Rheumatology, …
T cell responses to heat-shock protein 60: differential responses by CD4+ T cell subsets according to their expression of CD45 isotypes
…, JL Young, JC Goodall, JS Hill Gaston - The Journal of …, 1999 - journals.aai.org
We demonstrate that human T lymphocytes proliferate in vitro to highly purified human heat-shock
protein 60 (Hu. hsp60). The response to this self Ag was confined to the CD45RA+ RO…
protein 60 (Hu. hsp60). The response to this self Ag was confined to the CD45RA+ RO…
Spondylarthritis‐associated and non–spondylarthritis‐associated B27 subtypes differ in their dependence upon tapasin for surface expression and their incorporation …
…, L Ellis, JS Hill Gaston - Arthritis & Rheumatism …, 2006 - Wiley Online Library
Objective B27 subtypes associated with susceptibility to ankylosing spondylitis (AS), and
those reported not to be associated with AS, are found to differ in the amino acids that are …
those reported not to be associated with AS, are found to differ in the amino acids that are …