Objective. Patients with rheumatoid arthritis (RA) often have comorbidities that require multiple
medications. Several of these medications may alter the efficacy or increase the toxicity of …

Objective. Nontraumatic osteonecrosis (ON) is a well-recognized complication causing disability
and affecting quality of life in patients with systemic lupus erythematosus (SLE). The aim …

Background Scleromyositis (SM) is an emerging subset of myositis associated with features
of systemic sclerosis (SSc) but it is currently not recognized as a distinct histopathological …

Dermatomyositis (DM) is a major clinical subset of autoimmune myositis (AIM). The
characteristic DM rash (Gottron papules, heliotrope rash) and perifascicular atrophy at skeletal …

Objective To describe successful therapeutic strategies in statin-induced anti-HMGCR
myopathy. Methods Retrospective data from a cohort of 55 patients with statin-induced anti-…

Objective To examine whether anti‐Ro/SSA antibodies are associated with an increased risk
of corrected QT (QTc) prolongation, and to study the stability of this relationship over time. …

Objective To examine the association between smoking and cutaneous involvement in
systemic lupus erythematosus (SLE). Methods We analyzed data from a multicenter Canadian …

Objective To estimate the early prevalence of various electrocardiographic (EKG)
abnormalities in patients with systemic lupus erythematosus (SLE) and to evaluate possible …

Objective To describe systemic sclerosis (SSc) with myopathy in patients without classic SSc-specific
and SSc-overlap autoantibodies (aAbs), referred to as seronegative scleromyositis. …

Objective. To develop recommendations for the use of methotrexate (MTX) in patients with
rheumatoid arthritis. Methods. Canadian rheumatologists who participated in the international …