… LeRoy EC Medsger TA Jr Criteria for the classification of early systemic sclerosis. J …
Steen VD Medsger TA Jr Improvement in skin thickening in systemic sclerosis associated with …

Objective The 1980 American College of Rheumatology (ACR) classification criteria for
systemic sclerosis (SSc) lack sensitivity for early SSc and limited cutaneous SSc. The present …

Objective. Interstitial lung disease (ILD) is common in connective tissue disease (CTD) and
is the leading cause of mortality. Investigators have used certain outcome measures in …

Background We conducted a double-blind, randomized, placebo-controlled trial to determine
the effects of oral cyclophosphamide on lung function and health-related symptoms in …

Objectives To determine the causes and predictors of mortality in systemic sclerosis (SSc).
Methods Patients with SSc (n=5860) fulfilling the American College of Rheumatology criteria …

Objective Recurrent digital ulcers are a manifestation of vascular disease in patients with
systemic sclerosis (SSc; scleroderma) and lead to pain, impaired function, and tissue loss. We …

Objective Earlier detection of pulmonary arterial hypertension (PAH), a leading cause of death
in systemic sclerosis (SSc), facilitates earlier treatment. The objective of this study was to …

Objective To document disease activity and functional status in patients with scleroderma (systemic
sclerosis [SSc]) and Raynaud's phenomenon (RP) and to determine the sensitivity to …

… LeRoy EC, Medsger TA Jr. Criteria for the classification of early systemic sclerosis. J … Johnson
SR, Fransen J, Khanna D, Bacon M, van den Hoogen F, Medsger TA Jr, et al. Validation of …

Objective To test the hypothesis that systemic sclerosis (SSc) patients taking high‐dose D‐penicillamine
(D‐Pen) would have greater softening of skin, lower frequency of renal crisis, …