[HTML][HTML] Female sexual dysfunction: incidence, pathophysiology, evaluation, and treatment options

JR Berman, L Berman, I Goldstein - Urology, 1999 - goldjournal.net
Female sexual dysfunction is age-related, pro-gressive, and highly prevalent, affecting 30%
to 50% of women. 1–3 Based on the National Health and Social Life Survey of 1749 women, …

Vasculogenic female sexual dysfunction: vaginal engorgement and clitoral erectile insufficiency syndromes.

I Goldstein, JR Berman - International Journal of Impotence …, 1998 - europepmc.org
The first phase of the female sexual response, associated with neurotransmitter-mediated
vascular smooth muscle relaxation, results in increased vaginal lubrication, wall engorgement …

Physiology of female sexual function and dysfunction

JR Berman - International journal of impotence research, 2005 - nature.com
Female sexual dysfunction is age-related, progressive, and highly prevalent, affecting 30–50%
of American women. While there are emotional and relational elements to female sexual …

[HTML][HTML] Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan

N Libina, JR Berman, C Kenyon - Cell, 2003 - cell.com
In C. elegans, the transcription factor DAF-16 promotes longevity in response to reduced
insulin/IGF-1 signaling or germline ablation. In this study, we have asked how different tissues …

Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells

…, W Magis, NL Bray, T Wang, JR Berman… - Science translational …, 2016 - science.org
Genetic diseases of blood cells are prime candidates for treatment through ex vivo gene
editing of CD34 + hematopoietic stem/progenitor cells (HSPCs), and a variety of technologies …

Large multiallelic copy number variations in humans

RE Handsaker, V Van Doren, JR Berman… - Nature …, 2015 - nature.com
Thousands of genomic segments appear to be present in widely varying copy numbers in
different human genomes. We developed ways to use increasingly abundant whole-genome …

[HTML][HTML] Germ-cell loss extends C. elegans life span through regulation of DAF-16 by kri-1 and lipophilic-hormone signaling

JR Berman, C Kenyon - Cell, 2006 - cell.com
In C. elegans, removing the germ cells extends life span by triggering the nuclear localization
and activation of the DAF-16/FOXO transcription factor in the intestine. In this study, we …

Safety and efficacy of sildenafil citrate for the treatment of female sexual arousal disorder: a double-blind, placebo controlled study

JR Berman, LA Berman, SM Toler, J Gill… - The Journal of …, 2003 - auajournals.org
Purpose : We evaluated the efficacy and safety of sildenafil citrate in spontaneously or
surgically postmenopausal women with female sexual arousal disorder (FSAD). Materials and …

[HTML][HTML] Systematic quantification of HDR and NHEJ reveals effects of locus, nuclease, and cell type on genome-editing

Y Miyaoka, JR Berman, SB Cooper, SJ Mayerl… - Scientific reports, 2016 - nature.com
Precise genome-editing relies on the repair of sequence-specific nuclease-induced DNA
nicking or double-strand breaks (DSBs) by homology-directed repair (HDR). However, …

Multiplexed target detection using DNA-binding dye chemistry in droplet digital PCR

…, Y Ling, N Klitgord, GJ Carman, JR Berman… - Analytical …, 2013 - ACS Publications
Two years ago, we described the first droplet digital PCR (ddPCR) system aimed at empowering
all researchers with a tool that removes the substantial uncertainties associated with …