[HTML][HTML] Randomized assessment of rapid endovascular treatment of ischemic stroke
…, M Kelly, G Linares, JL Mandzia… - … England Journal of …, 2015 - Mass Medical Soc
Background Among patients with a proximal vessel occlusion in the anterior circulation, 60
to 80% of patients die within 90 days after stroke onset or do not regain functional …
to 80% of patients die within 90 days after stroke onset or do not regain functional …
Post-stroke depression, obstructive sleep apnea, and cognitive impairment: rationale for, and barriers to, routine screening
…, D Dowlatshahi, JL Mandzia… - … journal of stroke, 2016 - journals.sagepub.com
Stroke can cause neurological impairment ranging from mild to severe, but the impact of
stroke extends beyond the initial brain injury to include a complex interplay of devastating …
stroke extends beyond the initial brain injury to include a complex interplay of devastating …
Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial
…, BCV Campbell, R Chapot, J Teitelbaum, JL Mandzia… - The Lancet, 2020 - thelancet.com
Background Nerinetide, an eicosapeptide that interferes with post-synaptic density protein
95, is a neuroprotectant that is effective in preclinical stroke models of ischaemia-reperfusion. …
95, is a neuroprotectant that is effective in preclinical stroke models of ischaemia-reperfusion. …
Severe intracranial involvement in giant cell arteritis: 5 cases and literature review
…, NA Khalidi, C Pagnoux, JL Mandzia… - The Journal of …, 2016 - jrheum.org
Objective. Involvement of intracranial arteries in giant cell arteritis (GCA) is rare. We describe
the neurologic complications of intracranial GCA (IC GCA) and available treatment options. …
the neurologic complications of intracranial GCA (IC GCA) and available treatment options. …
COVID-19: stroke admissions, emergency department visits, and prevention clinic referrals
MB Bullrich, S Fridman, JL Mandzia, LM Mai… - Canadian Journal of …, 2020 - cambridge.org
We assessed the impact of the coronavirus disease 19 (COVID-19) pandemic on code stroke
activations in the emergency department, stroke unit admissions, and referrals to the stroke …
activations in the emergency department, stroke unit admissions, and referrals to the stroke …
Contrast echocardiography for detection of pulmonary arteriovenous malformations
…, RA Pugash, JA Clarke, SJ Hutchison, JL Mandzia… - American heart …, 2001 - Elsevier
Background Pulmonary arteriovenous malformations (PAVMs) lead to stroke, brain abscess,
and hemorrhage in hereditary hemorrhagic telangiectasia (HHT). The current screening …
and hemorrhage in hereditary hemorrhagic telangiectasia (HHT). The current screening …
Primary CNS vasculitis: a systematic review on clinical characteristics associated with abnormal biopsy and angiography
M Krawczyk, LJ Barra, LA Sposato, JL Mandzia - Autoimmunity Reviews, 2021 - Elsevier
Background Primary Central Nervous System Vasculitis (PCNSV) remains a diagnostic
challenge due to its variable and non-specific clinical manifestations. In part, the clinical …
challenge due to its variable and non-specific clinical manifestations. In part, the clinical …
Healthy life-year costs of treatment speed from arrival to endovascular thrombectomy in patients with ischemic stroke: a meta-analysis of individual patient data from 7 …
…, B Jankowitz, M Kelly, G Linares, JL Mandzia… - JAMA …, 2021 - jamanetwork.com
Importance The benefits of endovascular thrombectomy (EVT) are time dependent. Prior
studies may have underestimated the time-benefit association because time of onset is …
studies may have underestimated the time-benefit association because time of onset is …
Differences in stroke recurrence risk between atrial fibrillation detected on ECG and 14-day cardiac monitoring
…, D Ayan, AV Khaw, LM Mai, JL Mandzia… - Stroke, 2023 - Am Heart Assoc
BACKGROUND: Ischemic stroke and transient ischemic attack (TIA) standard-of-care
etiological investigations include an ECG and prolonged cardiac monitoring (PCM). Atrial …
etiological investigations include an ECG and prolonged cardiac monitoring (PCM). Atrial …
Assessment of discrepancies between follow-up infarct volume and 90-day outcomes among patients with ischemic stroke who received endovascular therapy
…, J Arsenault, R Kinnear, JL Mandzia… - JAMA network …, 2021 - jamanetwork.com
Importance Some patients have poor outcomes despite small infarcts after endovascular
therapy (EVT), while others with large infarcts do well. Understanding why these discrepancies …
therapy (EVT), while others with large infarcts do well. Understanding why these discrepancies …