A number of inflammatory disease states occur with greatly increased frequency in individuals
inheriting the human major histocompatibility complex class I allele HLA-B27. In a minority …

Objective. To investigate the response to therapy of entheseal abnormalities assessed with
power Doppler (PD) ultrasound (US) in spondyloarthropathies (SpA). Methods. A total of 327 …

… Address correspondence to José Luis Fernández-Sueiro, MD, Rheumatology Division, …
Fernández-Sueiro had full access to all of the data in the study and takes responsibility for …

Objective. The national registry of spondyloarthropathies (REGISPONSER) is launched to
classify patients with this group of diseases treated in Spanish rheumatology clinics. This …

Objective Osteoarthritis (OA) is a degenerative rheumatic disease that is associated with
extracellular matrix degradation and chondrocyte apoptosis in the articular cartilage. The role of …

Background: An erythrocyte sedimentation rate (ESR) of at least 40 mm/h is considered an
important requisite for the diagnosis of polymyalgia rheumatica (PMR). However, the relative …

Rats transgenic for the human MHC class I gene HLA-B27 are susceptible to a spontaneous
multisystem inflammatory disease that resembles human B27-associated disease. This …

Recent genome-wide association studies (GWASs) have identified >20 new loci associated
with the susceptibility to psoriasis vulgaris (PsV) risk. We investigated the association of PsV …

Objectives: Recent results have shown that the IL23R gene, coding for a subunit of the
interleukin-23 receptor, is strongly associated with autoimmunity. The aim of the current study was …

The association of endoplasmic reticulum aminopeptidase 2 (ERAP2) with ankylosing
spondylitis (AS) was recently described in the large International Genetics of AS Consortium …