Chronic infection with hepatitis C virus (HCV) is a leading indicator for liver disease. New
treatment options are becoming available, and there is a need to characterize the …

Objective Rituximab is an anti-CD20 monoclonal antibody targeting B cells, which has been
used with success in a wide variety of autoimmune diseases. The experience with this drug …

In this study, 1,833 systemic sclerosis (SSc) cases and 3,466 controls were genotyped with
the Immunochip array. Classical alleles, amino acid residues, and SNPs across the human …

Systemic lupus erythematosus (SLE) is a prototypic autoimmune disorder with a complex
pathogenesis in which genetic, hormonal and environmental factors have a role. Rare …

Objective. To evaluate systemic involvement in primary SS in a large cohort of Spanish
patients using the EULAR-SS disease activity index (ESSDAI) definitions. Methods. Systemic …

We conducted a large-scale genetic analysis on giant cell arteritis (GCA), a polygenic
immune-mediated vasculitis. A case-control cohort, comprising 1,651 case subjects with GCA and …

… de Ramón3, JL Callejas4, A. Martínez-Berriotxoa5, L. Pallarés6, L. … García-Hernández,
MD, PhD Enrique de Ramón, MD, PhD José Luis Callejas, MD, PhD Agustín Martínez-Berriotxoa …

The aim of this study was to describe the clinical characteristics of ANCA-associated vasculitides
(AAV) at presentation, in a wide cohort of Spanish patients, and to analyze the impact of …

Background & Aims The success of direct-acting antivirals (DAA) against hepatitis C is a
major breakthrough in hepatology. Until now, however, there are very few data on the effect of …

Objective. To describe the experience of two tertiary Spanish centres (Hospital Clínico San
Cecilio, Granada and Hospital Clínic, Barcelona) with the use of adalimumab for the …