[HTML][HTML] The COMET handbook: version 1.0
The selection of appropriate outcomes is crucial when designing clinical trials in order to
compare the effects of different interventions directly. For the findings to influence policy and …
compare the effects of different interventions directly. For the findings to influence policy and …
[HTML][HTML] Systematic review of the empirical evidence of study publication bias and outcome reporting bias—an updated review
K Dwan, C Gamble, PR Williamson, JJ Kirkham… - PloS one, 2013 - journals.plos.org
Background The increased use of meta-analysis in systematic reviews of healthcare
interventions has highlighted several types of bias that can arise during the completion of a …
interventions has highlighted several types of bias that can arise during the completion of a …
[HTML][HTML] Core outcome Set-STAndards for development: the COS-STAD recommendations
JJ Kirkham, K Davis, DG Altman, JM Blazeby… - PLoS …, 2017 - journals.plos.org
Background The use of core outcome sets (COS) ensures that researchers measure and
report those outcomes that are most likely to be relevant to users of their research. Several …
report those outcomes that are most likely to be relevant to users of their research. Several …
RoB 2: a revised tool for assessing risk of bias in randomised trials
Assessment of risk of bias is regarded as an essential component of a systematic review on
the effects of an intervention. The most commonly used tool for randomised trials is the …
the effects of an intervention. The most commonly used tool for randomised trials is the …
The impact of outcome reporting bias in randomised controlled trials on a cohort of systematic reviews
Objective To examine the prevalence of outcome reporting bias—the selection for publication
of a subset of the original recorded outcome variables on the basis of the results—and its …
of a subset of the original recorded outcome variables on the basis of the results—and its …
[HTML][HTML] Core outcome set–STAndards for reporting: the COS-STAR statement
JJ Kirkham, S Gorst, DG Altman, JM Blazeby… - PLoS …, 2016 - journals.plos.org
Background Core outcome sets (COS) can enhance the relevance of research by ensuring
that outcomes of importance to health service users and other people making choices about …
that outcomes of importance to health service users and other people making choices about …
[HTML][HTML] Development and inter-rater reliability of the Liverpool adverse drug reaction causality assessment tool
RM Gallagher, JJ Kirkham, JR Mason, KA Bird… - PloS one, 2011 - journals.plos.org
Aim To develop and test a new adverse drug reaction (ADR) causality assessment tool (CAT).
A comparison between seven assessors of a new CAT, formulated by an expert focus …
A comparison between seven assessors of a new CAT, formulated by an expert focus …
Frequency and reasons for outcome reporting bias in clinical trials: interviews with trialists
RESEARCH Page 1 RESEARCH Frequency and reasons for outcome reporting bias in
clinical trials: interviews with trialists RMD Smyth, research associate,1,2 JJ Kirkham, research …
clinical trials: interviews with trialists RMD Smyth, research associate,1,2 JJ Kirkham, research …
Selective reporting bias of harm outcomes within studies: findings from a cohort of systematic reviews
Objective To determine the extent and nature of selective non-reporting of harm outcomes
in clinical studies that were eligible for inclusion in a cohort of systematic reviews. Design …
in clinical studies that were eligible for inclusion in a cohort of systematic reviews. Design …
[HTML][HTML] Can a core outcome set improve the quality of systematic reviews?–a survey of the Co-ordinating Editors of Cochrane Review Groups
JJ Kirkham, E Gargon, M Clarke, PR Williamson - Trials, 2013 - Springer
Background Missing outcome data or the inconsistent reporting of outcome data in clinical
research can affect the quality of evidence within a systematic review. A potential solution is …
research can affect the quality of evidence within a systematic review. A potential solution is …