Optimising drug treatment for elderly people: the prescribing cascade

PA Rochon, JH Gurwitz - Bmj, 1997 - bmj.com
The most frequent medical intervention performed by a doctor is the writing of a prescription.
Because chronic illness increases with advancing age, older people are more likely to have …

Patients at-risk for cost-related medication nonadherence: a review of the literature

BA Briesacher, JH Gurwitz, SB Soumerai - Journal of general internal …, 2007 - Springer
Objective Up to 32% of older patients take less medication than prescribed to avoid costs,
yet a comprehensive assessment of risk factors for cost-related nonadherence (CRN) is not …

The effect of computerized physician order entry with clinical decision support on the rates of adverse drug events: a systematic review

JI Wolfstadt, JH Gurwitz, TS Field, M Lee… - Journal of general …, 2008 - Springer
Context Computerized physician order entry (CPOE) with clinical decision support (CDS) has
been promoted as an effective strategy to prevent the development of a drug injury defined …

Incidence and preventability of adverse drug events among older persons in the ambulatory setting

JH Gurwitz, TS Field, LR Harrold, J Rothschild… - Jama, 2003 - jamanetwork.com
Context Adverse drug events, especially those that may be preventable, are among the most
serious concerns about medication use in older persons cared for in the ambulatory clinical …

Incidence of hospitalized rhabdomyolysis in patients treated with lipid-lowering drugs

…, SE Andrade, SD Schech, L La Grenade, JH Gurwitz… - Jama, 2004 - jamanetwork.com
ContextLipid-lowering agents are widely prescribed in the United States. Reliable estimates
of rhabdomyolysis risk with various lipid-lowering agents are not available.ObjectiveTo …

Incidence and preventability of adverse drug events in nursing homes

JH Gurwitz, TS Field, J Avorn, D McCormick… - The American journal of …, 2000 - Elsevier
PURPOSE: Adverse drug events, especially those that may have been preventable, are
among the most serious concerns about medication use in nursing homes. We studied the …

Reduction of bacteriuria and pyuria after ingestion of cranberry juice

J Avorn, M Monane, JH Gurwitz, RJ Glynn… - Jama, 1994 - jamanetwork.com
Objective. —To determine the effect of regular intake of cranberry juice beverage on
bacteriuria and pyuria in elderly women. Design. —Randomized, double-blind, placebo-controlled …

Antipsychotic drug use and mortality in older adults with dementia

…, HD Fischer, N Herrmann, JH Gurwitz… - Annals of internal …, 2007 - acpjournals.org
Background: Antipsychotic drugs are widely used to manage behavioral and psychological
symptoms in dementia despite concerns about their safety. Objective: To examine the …

Prescription drug use in pregnancy

SE Andrade, JH Gurwitz, RL Davis, KA Chan… - American journal of …, 2004 - Elsevier
OBJECTIVE: The purpose of this study was to provide information on the prevalence of the
use of prescription drugs among pregnant women in the United States. STUDY DESIGN: A …

The exclusion of the elderly and women from clinical trials in acute myocardial infarction

JH Gurwitz, NF Col, J Avorn - Jama, 1992 - jamanetwork.com
Objective. —To determine the extent to which the elderly have been excluded from trials of
drug therapies used in the treatment of acute myocardial infarction, to identify factors …