Haematopoietic stem cell transplantation for autoimmune diseases

JF Swart, EM Delemarre, F Van Wijk… - Nature Reviews …, 2017 - nature.com
Autologous haematopoietic stem cell transplantation (HSCT) is the only treatment that is
able to induce long-term, drug-free and symptom-free remission in several refractory …

Treating juvenile idiopathic arthritis to target: recommendations of an international task force

…, S Sawhney, C Scott, S Shenoi, JF Swart… - Annals of the …, 2018 - ard.bmj.com
Recent therapeutic advances in juvenile idiopathic arthritis (JIA) have made remission an
achievable goal for most patients. Reaching this target leads to improved outcomes. The …

Immunogenicity of biologic agents in juvenile idiopathic arthritis: a systematic review and meta-analysis

…, EM Van Maarseveen, JF Swart - Rheumatology, 2019 - academic.oup.com
Objective The clinical impact of anti-drug antibodies (ADAbs) in paediatric patients with JIA
remains unknown. This systematic review and meta-analysis aimed to summarize the …

Understanding inflammation in juvenile idiopathic arthritis: How immune biomarkers guide clinical strategies in the systemic onset subtype

JF Swart, S de Roock… - European journal of …, 2016 - Wiley Online Library
The translation of basic insight in immunological mechanisms underlying inflammation into
clinical practice of inflammatory diseases is still challenging. Here we describe how—through …

Predictors of health‐related quality of life in children and adolescents with juvenile idiopathic arthritis: results from a web‐based survey

…, KM Dolman, JF Swart… - Arthritis care & …, 2012 - Wiley Online Library
Objective Children with juvenile idiopathic arthritis (JIA) experience functional impairment
due to joint manifestations of the disease. The aim of our present study was to assess health‐…

Factors associated with treatment response to etanercept in juvenile idiopathic arthritis

…, SL Gorter, KM Dolman, JF Swart… - Jama, 2011 - jamanetwork.com
Context Since the introduction of biologic therapies, the pharmacological treatment approach
for juvenile idiopathic arthritis (JIA) has changed substantially, with achievement of inactive …

[PDF][PDF] Treatment to target using recombinant interleukin‐1 receptor antagonist as first‐line monotherapy in new‐onset systemic juvenile idiopathic arthritis: results from …

…, EHP van Dijkhuizen, JF Swart… - Arthritis & …, 2019 - Wiley Online Library
Objective Systemic juvenile idiopathic arthritis (JIA) is a multifactorial autoinflammatory disease
with a historically poor prognosis. With current treatment regimens, approximately half of …

Phenotypic variability and disparities in treatment and outcomes of childhood arthritis throughout the world: an observational cohort study

…, R Shiari, E Smolewska, B Sozeri, JF Swart… - The Lancet Child & …, 2019 - thelancet.com
Background To our knowledge, the characteristics and burden of childhood arthritis have
never been studied on a worldwide basis. We aimed to investigate, with a cross-sectional study…

Clinical Juvenile Arthritis Disease Activity Score proves to be a useful tool in treat-to-target therapy in juvenile idiopathic arthritis

JF Swart, EHP van Dijkhuizen, NM Wulffraat… - Annals of the …, 2018 - ard.bmj.com
Objectives To assess if the Juvenile Arthritis Disease Activity Score (JADAS71) could be
used to correctly identify patients with juvenile idiopathic arthritis (JIA) in need of antitumour …

Definition and validation of the American College of Rheumatology 2021 juvenile arthritis disease activity score cutoffs for disease activity states in juvenile idiopathic …

…, A Alongi, M Mazzoni, JF Swart… - Arthritis & …, 2021 - Wiley Online Library
… Notably, the new cutoffs are closer to the JADAS thresholds identified by Swart et al for
treatment escalation from a cohort of JIA patients seen at an academic center (28). …