There is no clear consensus regarding the frequency (and hence, the risk), of dyskinesias or
motor fluctuations during chronic levodopa therapy for Parkinson's disease (PD). Multiple …

REM sleep behaviour disorder (RBD) is a parasomnia characterized by the loss of normal
skeletal muscle atonia during REM sleep with prominent motor activity accompanying …

A rapidly growing literature strongly suggests that exercise, specifically aerobic exercise,
may attenuate cognitive impairment and reduce dementia risk. We used PubMed (keywords …

Objective: There is increasing laboratory evidence for a neuroprotective effect of estrogen;
however, the clinical and epidemiologic evidence remains limited and conflicting. We studied …

… Analysis and interpretation of data: Dodd, Klos, Geda, Josephs, and Ahlskog. Drafting of
the manuscript: Dodd, Klos, and Ahlskog. Critical revision of the manuscript for important …

Parkinson disease (PD) is progressive, with dementia and medication-refractory motor
problems common reasons for late-stage nursing-home placement. Increasing evidence …

Objective To investigate the neuropathologic substrate for dementia occurring late in
Parkinson disease (PD). Design We identified 13 patients with a clinical diagnosis of PD who …

We studied the association between preceding psychiatric disorders and Parkinson's disease
(PD) using a case‐control design. We used the medical records‐linkage system of the …

Background: Early reports suggested that corticobasal degeneration (CBD) is a distinct
clinicopathologic entity. Because patients have had a fairly consistent constellation of clinical and …

Objective: To determine if synucleinopathy pathology is related to REM sleep behavior
disorder (RBD) plus dementia or parkinsonism. Methods: The clinical and neuropathologic …