User profiles for J S Hill Gaston
Hill Gastonprofessor rheumatology university of cambridge Verified email at medschl.cam.ac.uk Cited by 4145 |
Arthritis associated with enteric infection
JSH Gaston, MS Lillicrap - Best practice & research Clinical rheumatology, 2003 - Elsevier
Reactive arthritis is classically seen following infection with enteric pathogens such as Yersinia,
Salmonella, Campylobacter and Shigella. Inflammatory arthritis has also been described …
Salmonella, Campylobacter and Shigella. Inflammatory arthritis has also been described …
Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis
…, JC Goodall, JS Hill Gaston - Arthritis & Rheumatism …, 2009 - Wiley Online Library
… JS Hill Gaston … JS Hill Gaston … Gaston had full access to all of the data in the study
and takes responsibility for the integrity of the data and the accuracy of the data analysis. …
and takes responsibility for the integrity of the data and the accuracy of the data analysis. …
Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility
…, H Marzo-Ortega, P Bowness, K Gaffney, JSH Gaston… - Nature …, 2011 - nature.com
Ankylosing spondylitis is a common form of inflammatory arthritis predominantly affecting
the spine and pelvis that occurs in approximately 5 out of 1,000 adults of European descent. …
the spine and pelvis that occurs in approximately 5 out of 1,000 adults of European descent. …
Endoplasmic reticulum stress-induced transcription factor, CHOP, is crucial for dendritic cell IL-23 expression
…, L Ellis, V Saudek, JSH Gaston - Proceedings of the …, 2010 - National Acad Sciences
The endoplasmic reticulum (ER) stress response detects malfunctions in cellular physiology,
and microbial pattern recognition receptors recognize external threats posed by infectious …
and microbial pattern recognition receptors recognize external threats posed by infectious …
Clinical phenotype is related to HLA genotype in the peripheral arthropathies of inflammatory bowel disease
…, S Thiyagaraja, KI Welsh, BP Wordsworth, JSH Gaston… - Gastroenterology, 2000 - Elsevier
Background & Aims: The detection of phenotype-determining genes as opposed to disease
susceptibility genes requires precise phenotypic characterization of patients. Peripheral …
susceptibility genes requires precise phenotypic characterization of patients. Peripheral …
PI3K p110δ regulates T-cell cytokine production during primary and secondary immune responses in mice and humans
…, B Twomey, J Clark, JSH Gaston… - Blood, The Journal …, 2010 - ashpublications.org
We have previously described critical and nonredundant roles for the phosphoinositide 3-kinase
p110δ during the activation and differentiation of naive T cells, and p110δ inhibitors are …
p110δ during the activation and differentiation of naive T cells, and p110δ inhibitors are …
Reverse transcriptase-PCR analysis of bacterial rRNA for detection and characterization of bacterial species in arthritis synovial tissue
…, ED Zanders, JSH Gaston, JS Crowe - Infection and …, 2000 - Am Soc Microbiol
Onset of rheumatoid arthritis (RA) is widely believed to be preceded by exposure to some
environmental trigger such as bacterial infectious agents. The influence of bacteria on RA …
environmental trigger such as bacterial infectious agents. The influence of bacteria on RA …
[HTML][HTML] β-Glucan size controls dectin-1-mediated immune responses in human dendritic cells by regulating IL-1β production
…, R Chee, DL Williams, JS Hill Gaston… - Frontiers in …, 2017 - frontiersin.org
Dectin-1/CLEC7A is a pattern recognition receptor that recognizes β-1,3 glucans, and its
stimulation initiates signaling events characterized by the production of inflammatory cytokines …
stimulation initiates signaling events characterized by the production of inflammatory cytokines …
CD27 expression discriminates between regulatory and non‐regulatory cells after expansion of human peripheral blood CD4+ CD25+ cells
…, TNF Shaw, LB Jarvis, G Kaur, JS Hill Gaston - …, 2007 - Wiley Online Library
It is clear that regulatory T cells (Treg) have an important role in preventing autoimmunity
and modulating responses to pathogens. Full characterization of Treg cell function in human …
and modulating responses to pathogens. Full characterization of Treg cell function in human …
The role of T-Iymphocytes in rheumatoid arthritis
M Salmon, JS Hill Gaston - British medical bulletin, 1995 - academic.oup.com
The role of T lymphocytes in the pathology of rheumatoid arthritis (RA) is controversial. To
some extent this has resulted from contradictory data, but even where specific points of fact are …
some extent this has resulted from contradictory data, but even where specific points of fact are …